Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Rivaroxaban
Drug ID BADD_D01954
Description Rivaroxaban is an anticoagulant and the first orally active direct factor Xa inhibitor. Unlike warfarin, routine lab monitoring of INR is not necessary. However there is no antidote available in the event of a major bleed. Only the 10 mg tablet can be taken without regard to food. The 15 mg and 20 mg tablet should be taken with food. FDA approved on July 1, 2011.
Indications and Usage Not Available
Marketing Status Prescription
ATC Code B01AF01
DrugBank ID DB06228
KEGG ID D07086
MeSH ID D000069552
PubChem ID 9875401
TTD Drug ID D0KG3R
NDC Product Code 50090-3625; 50458-579; 50458-575; 65015-898; 58032-2029; 55154-1424; 53296-0109; 14799-2023; 55111-966; 76072-1008; 47848-039; 55154-1423; 14501-0079; 65727-050; 52286-0025; 59285-009; 65862-971; 16436-0109; 75945-050; 50090-4468; 53104-7730; 50090-3639; 53747-068; 66022-0203; 50090-4469; 50458-580; 64220-176; 63415-0523; 64552-4049; 50458-578; 46708-899; 82513-0001; 66174-0087; 72969-109; 66039-913; 50458-584; 65372-1193; 50458-577; 55154-1422; 69218-0500
Synonyms Rivaroxaban | 5-chloro-N-(((5S)-2-oxo-3-(4-(3-oxomorpholin-4-yl)phenyl)-1,3-oxazolidin-5-yl)methyl)thiophene-2-carboxamide | Xarelto | BAY 59-7939 | BAY 59 7939 | BAY 597939
Chemical Information
Molecular Formula C19H18ClN3O5S
CAS Registry Number 366789-02-8
SMILES C1COCC(=O)N1C2=CC=C(C=C2)N3CC(OC3=O)CNC(=O)C4=CC=C(S4)Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Renal embolism24.01.11.003; 20.01.07.0140.000233%Not Available
Post procedural pulmonary embolism24.01.06.009; 22.06.02.008; 12.02.07.0120.002142%Not Available
Multimorbidity08.01.03.0750.000279%Not Available
Angina bullosa haemorrhagica24.07.02.040; 07.05.01.0130.000535%Not Available
Thyroid haemorrhage05.02.01.005; 24.07.01.0830.000535%Not Available
Haemorrhagic arteriovenous malformation24.03.03.032; 03.07.03.0080.004819%Not Available
Breast haematoma24.07.03.020; 21.05.05.0130.000535%Not Available
Gastrointestinal telangiectasia24.03.03.030; 07.15.04.0060.000714%Not Available
Age-related macular degeneration06.09.03.0180.000714%Not Available
Tooth socket haemorrhage24.07.02.059; 07.09.05.0170.000535%Not Available
Thalamic infarction24.04.06.041; 17.08.01.0610.000714%Not Available
Eyelid haematoma24.07.05.013; 23.06.07.007; 12.01.04.025; 06.07.05.0020.000279%Not Available
Dermo-hypodermitis23.09.01.021; 11.01.12.0210.000357%Not Available
Ligament rupture15.07.02.008; 12.01.07.014--Not Available
Venous haemorrhage24.07.01.0870.000714%Not Available
Paradoxical embolism24.01.01.0310.000357%Not Available
Post procedural haematuria24.07.01.076; 20.02.01.033; 12.02.10.0070.001249%Not Available
Stress cardiomyopathy24.04.04.026; 02.04.01.012--Not Available
Post procedural stroke24.04.06.039; 17.08.01.057; 12.02.04.0100.000466%Not Available
Post procedural sepsis12.02.05.049; 11.01.11.0130.000140%Not Available
Myocardial strain13.14.02.0190.000357%Not Available
Basal ganglia haemorrhage24.07.04.021; 17.08.01.0390.002514%Not Available
Carotid arteriosclerosis24.04.06.031; 17.08.02.0150.000357%Not Available
Left atrial dilatation02.04.02.025--Not Available
Coeliac artery stenosis24.04.08.015; 07.15.02.0120.000357%Not Available
Thrombotic cerebral infarction24.01.04.017; 17.08.01.0630.001249%Not Available
Abdominal wall haematoma24.07.02.039; 07.16.05.0050.008210%Not Available
Heart valve incompetence02.07.02.0030.000357%Not Available
Dieulafoy's vascular malformation24.03.03.025; 07.15.04.0020.000535%Not Available
Aortic intramural haematoma24.02.03.0040.000140%Not Available
The 54th Page    First    Pre   54 55 56    Next   Last    Total 56 Pages