Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Risedronic acid
Drug ID BADD_D01950
Description Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label][A959].
Indications and Usage Risedronic acid is indicated for the treatment of osteoperosis in men, treatment of Paget's disease, treatment and prevention of osteoperosis in postmenopausal women, and treatment and prevention of glucocorticoid-induced osteoperosis[FDA Label].
Marketing Status approved; investigational
ATC Code M05BA07
DrugBank ID DB00884
KEGG ID D08484
MeSH ID D000068296
PubChem ID 5245
TTD Drug ID D0PA5S
NDC Product Code Not Available
UNII KM2Z91756Z
Synonyms Risedronic Acid | 1-Hydroxy-2-(3-pyridyl)ethylidene diphosphonate | Atelvia | Risedronate Sodium | 2-(3-pyridinyl)-1-hydroxyethylidene-bisphosphonate | 2-(3-pyridinyl)-1-hydroxyethylidenebisphosphonate | Risedronic Acid, Monosodium Salt | Actonel | Risedronate | Bisphosphonate Risedronate Sodium | Risedronate Sodium, Bisphosphonate | Sodium, Bisphosphonate Risedronate
Chemical Information
Molecular Formula C7H11NO7P2
CAS Registry Number 105462-24-6
SMILES C1=CC(=CN=C1)CC(O)(P(=O)(O)O)P(=O)(O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Inner ear disorder04.04.02.002--Not Available
Polyp16.02.02.005; 08.01.06.010--Not Available
Blood disorder01.05.01.004--Not Available
Drug intolerance08.06.01.013--Not Available
Hepatobiliary disease09.01.08.003--Not Available
Poor quality sleep19.02.05.005; 17.15.04.002--Not Available
Cystitis noninfective20.03.02.001--
Osteonecrosis of jaw24.04.05.005; 15.02.04.010--
Bone loss15.02.04.020--Not Available
Oral disorder07.05.01.005--Not Available
Gastrointestinal tract irritation07.08.03.008--Not Available
Intervertebral disc space narrowing15.10.01.007--Not Available
Foot deformity15.10.03.005--Not Available
Spondylolisthesis12.04.04.008; 15.10.04.004--Not Available
Spinal pain17.10.01.020; 15.02.01.008; 08.01.08.030--Not Available
Large intestinal stenosis07.13.03.004--
Gait inability17.02.05.069; 08.01.02.011--Not Available
Muscle discomfort15.05.03.037--Not Available
Pharyngeal swelling22.04.05.028--Not Available
Taste disorder17.02.07.029; 07.14.03.004--Not Available
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