Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Risedronic acid
Drug ID BADD_D01950
Description Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label][A959].
Indications and Usage Risedronic acid is indicated for the treatment of osteoperosis in men, treatment of Paget's disease, treatment and prevention of osteoperosis in postmenopausal women, and treatment and prevention of glucocorticoid-induced osteoperosis[FDA Label].
Marketing Status approved; investigational
ATC Code M05BA07
DrugBank ID DB00884
KEGG ID D08484
MeSH ID D000068296
PubChem ID 5245
TTD Drug ID D0PA5S
NDC Product Code Not Available
UNII KM2Z91756Z
Synonyms Risedronic Acid | 1-Hydroxy-2-(3-pyridyl)ethylidene diphosphonate | Atelvia | Risedronate Sodium | 2-(3-pyridinyl)-1-hydroxyethylidene-bisphosphonate | 2-(3-pyridinyl)-1-hydroxyethylidenebisphosphonate | Risedronic Acid, Monosodium Salt | Actonel | Risedronate | Bisphosphonate Risedronate Sodium | Risedronate Sodium, Bisphosphonate | Sodium, Bisphosphonate Risedronate
Chemical Information
Molecular Formula C7H11NO7P2
CAS Registry Number 105462-24-6
SMILES C1=CC(=CN=C1)CC(O)(P(=O)(O)O)P(=O)(O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Skin cancer23.08.02.002; 16.03.02.002--Not Available
Skin disorder23.03.03.007--Not Available
Skin irritation23.03.04.009--Not Available
Skin reaction10.01.03.019; 23.03.03.013--Not Available
Sleep disorder19.02.04.001--Not Available
Swelling08.01.03.015--Not Available
Swelling face08.01.03.100; 23.04.01.018; 10.01.05.018--Not Available
Swollen tongue23.04.01.014; 10.01.05.015; 07.14.02.003--Not Available
Syncope17.02.04.008; 02.11.04.015; 24.06.02.012--
Tendon disorder12.01.07.019; 15.07.01.002--Not Available
Tendonitis15.07.01.003; 12.01.07.007--Not Available
Throat irritation22.12.03.029; 07.05.05.037--Not Available
Thrombosis24.01.01.006--Not Available
Tinnitus17.04.07.004; 04.04.01.002--
Tooth disorder07.09.05.001--Not Available
Tooth loss12.01.17.026; 07.09.09.001--Not Available
Toothache07.09.06.001--
Ulcer08.03.06.001--Not Available
Upper respiratory tract infection22.07.03.011; 11.01.13.009--
Urethral disorder20.07.01.002--Not Available
Urinary tract disorder20.08.01.001--Not Available
Urinary tract infection20.08.02.001; 11.01.14.004--
Urticaria10.01.06.001; 23.04.02.001--
Uveitis10.02.01.023; 06.04.03.003--
Vertigo17.02.12.002; 04.04.01.003--
Vision blurred06.02.06.007; 17.17.01.010--
Visual impairment06.02.10.013--Not Available
Vomiting07.01.07.003--
Mobility decreased15.03.05.023; 17.02.05.018; 08.01.03.030--Not Available
Onychoclasis23.02.05.005--Not Available
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