Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Rimexolone
Drug ID BADD_D01946
Description Rimexolone is a 1% eye drop solution is a glucocorticoid steroid. It is used to treat inflammation in the eye. It is marketed as Vexol.
Indications and Usage For the treatment of postoperative inflammation following ocular surgery and in the treatment of anterior uveitis.
Marketing Status Discontinued
ATC Code H02AB12; S01BA13
DrugBank ID DB00896
KEGG ID D05729
MeSH ID C013769
PubChem ID 5311412
TTD Drug ID D0D2TN
NDC Product Code 60870-0423
Synonyms rimexolone | 11 beta-hydroxy-16 alpha,17 alpha,21-trimethylpregna-1,4-diene-3,20-dione | Rimexel | Vexol | Org 6216 | Org-6216
Chemical Information
Molecular Formula C24H34O3
CAS Registry Number 49697-38-3
SMILES CCC(=O)C1(C(CC2C1(CC(C3C2CCC4=CC(=O)C=CC34C)O)C)C)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Vital dye staining cornea present13.07.04.010--Not Available
Sticky skin23.03.03.019--Not Available
Eyelid margin crusting23.03.03.029; 06.04.04.005--Not Available
Nerve injury17.02.10.007; 12.01.12.002--Not Available
Corneal thinning06.06.03.009--Not Available
Sensation of foreign body08.01.09.002--Not Available
Ulcerative keratitis10.02.01.021; 06.04.02.004--
Perforation08.01.03.058--Not Available
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