Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Regadenoson
Drug ID BADD_D01921
Description Regadenoson is an A2A adenosine receptor agonist that causes coronary vasodilation and used for myocardial perfusion imagining. Manufactured by Astellas and FDA approved April 10, 2008.
Indications and Usage Diagnostic agent for radionuclide myocardial perfusion imaging (MPI)
Marketing Status approved; investigational
ATC Code C01EB21
DrugBank ID DB06213
KEGG ID D05711
MeSH ID C430916
PubChem ID 219024
TTD Drug ID D0XE1C
NDC Product Code 55150-443; 0409-1401; 76329-3321; 42973-229; 76055-0024; 60505-6116; 72611-874; 59285-029; 69766-103; 68083-175; 16729-477; 71288-201; 0641-6253; 65129-1331; 43598-616; 0469-6501; 62147-0220; 36000-364
UNII 2XLN4Y044H
Synonyms regadenoson | Lexiscan | CVT 3146 | CVT3146 | CVT-3146
Chemical Information
Molecular Formula C15H18N8O5
CAS Registry Number 313348-27-5
SMILES CNC(=O)C1=CN(N=C1)C2=NC(=C3C(=N2)N(C=N3)C4C(C(C(O4)CO)O)O)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Shock24.06.02.002--Not Available
Sinoatrial block02.03.01.010--Not Available
Sinus arrest02.03.03.0070.000313%Not Available
Sinus bradycardia02.03.03.0090.000085%
Skin discolouration23.03.03.0050.000186%Not Available
Skin disorder23.03.03.007--Not Available
Somnolence17.02.04.006; 19.02.05.003--
Supraventricular tachycardia02.03.03.0120.000211%
Swelling08.01.03.0150.000863%Not Available
Swollen tongue23.04.01.014; 07.14.02.003; 10.01.05.0150.000085%Not Available
Syncope24.06.02.012; 17.02.04.008; 02.11.04.0150.000567%
Tachycardia02.03.02.0070.000888%Not Available
Tachypnoea22.02.01.014--Not Available
Throat irritation22.12.03.029; 07.05.05.037--Not Available
Throat tightness22.12.03.031; 19.01.02.0050.000169%Not Available
Tinnitus04.04.01.002; 17.04.07.004--
Transient ischaemic attack24.04.06.005; 17.08.04.0010.000169%
Tremor17.01.06.0020.003662%
Unresponsive to stimuli17.02.05.0310.000778%Not Available
Urinary incontinence20.02.02.010; 17.05.01.0080.000085%
Urticaria10.01.06.001; 23.04.02.0010.000888%
Ventricular arrhythmia02.03.04.006--
Ventricular extrasystoles02.03.04.0070.000085%Not Available
Ventricular tachycardia02.03.04.0100.000169%
Vision blurred06.02.06.007; 17.17.01.010--
Vomiting07.01.07.0030.007925%
Vomiting projectile07.01.07.0120.000288%Not Available
Wandering pacemaker02.03.03.018--Not Available
Wheezing22.03.01.0090.000127%
Mental status changes19.07.01.0010.000211%Not Available
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