Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Rasburicase
Drug ID BADD_D01917
Description Rasburicase is a recombinant urate-oxidase enzyme produced by a genetically modified Saccharomyces cerevisiae strain. The cDNA coding for rasburicase was cloned from a strain of _Aspergillus flavus_.
Indications and Usage For treatment of hyperuricemia, reduces elevated plasma uric acid levels (from chemotherapy)
Marketing Status Prescription
ATC Code V03AF07
DrugBank ID DB00049
KEGG ID D05704
MeSH ID C469709
PubChem ID Not Available
TTD Drug ID D08LJP
NDC Product Code 0024-5151; 0024-5150
Synonyms rasburicase | Elitek | Fasturtec
Chemical Information
Molecular Formula Not Available
CAS Registry Number 134774-45-1
SMILES Not Available
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Haemolytic anaemiaGlucose-6-phosphate 1-dehydrogenaseP11413T6348411842483; 12673464; 12942574
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal infection11.01.07.014; 07.19.02.007--
Antibody test positive13.06.03.001--Not Available
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