Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Raltegravir
Drug ID BADD_D01905
Description Raltegravir is an antiretroviral drug produced by Merck & Co., used to treat HIV infection. It received approval by the U.S. Food and Drug Administration (FDA) on 12 October 2007, the first of a new class of HIV drugs, the integrase inhibitors, to receive such approval.
Indications and Usage For the treatment of HIV-1 infection in conjunction with other antiretrovirals.
Marketing Status Prescription
ATC Code J05AJ01
DrugBank ID DB06817
KEGG ID D06676
MeSH ID D000068898
PubChem ID 54671008
TTD Drug ID D0I1FQ
NDC Product Code 65977-0049; 70518-1621; 17381-749; 68071-2113; 0006-3080; 0006-0477; 0006-0473; 0006-0227; 50090-1085; 0006-3603
Synonyms Raltegravir Potassium | Potassium, Raltegravir | Raltegravir | MK 0518 | 0518, MK | MK0518 | MK-0518 | Isentress
Chemical Information
Molecular Formula C20H21FN6O5
CAS Registry Number 518048-05-0
SMILES CC1=NN=C(O1)C(=O)NC(C)(C)C2=NC(=C(C(=O)N2C)O)C(=O)NCC3=CC=C(C=C3)F
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Pyelocaliectasis20.01.06.0110.011331%Not Available
Viral load increased13.08.03.0350.015108%Not Available
Viral mutation identified13.08.03.0360.007554%Not Available
Virologic failure08.06.01.034; 11.01.08.0620.113307%Not Available
Cerebral calcification17.11.01.0120.018884%Not Available
Congenital skin dimples23.07.05.006; 03.05.01.0170.007554%Not Available
Lenticulostriatal vasculopathy17.08.02.022; 24.03.05.013; 18.04.04.0090.004926%Not Available
Poor feeding infant18.04.06.006; 14.03.02.0220.007554%Not Available
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