| Pharmaceutical Information |
| Drug Name |
Pyrilamine |
| Drug ID |
BADD_D01885 |
| Description |
Mepyramine, or pyrilamine, targets the H1 receptor. It is a first generation antihistamine. However, it rapidly permeates the brain and so often causes drowsiness as a side effect. It has been found in over-the-counter combination products for colds and menstrual symptoms, but is considered to be an unapproved prescription medication used for cough, cold, or allergic conditions. |
| Indications and Usage |
Mepyramine is a first generation antihistamine used in treating allergies, ymptomatic relief of hypersensitivity reaction, and in pruritic skin disorders. |
| Marketing Status |
Discontinued |
| ATC Code |
D04AA02; R06AC01 |
| DrugBank ID |
DB06691
|
| KEGG ID |
D08183
|
| MeSH ID |
D011738
|
| PubChem ID |
4992
|
| TTD Drug ID |
D08JZS
|
| NDC Product Code |
Not Available |
| Synonyms |
Pyrilamine | Mepyramine | Pyranisamine | Kriptin | Mepyramine Maleate | Maleate, Mepyramine | Pyrilamine Maleate | Maleate, Pyrilamine | Boots Bite & Sting Relief | Anthisan |
|
| Chemical Information |
| Molecular Formula |
C17H23N3O |
| CAS Registry Number |
91-84-9 |
| SMILES |
CN(C)CCN(CC1=CC=C(C=C1)OC)C2=CC=CC=N2 |
| Chemical Structure |
|
|
| ADR Related Proteins Induced by Drug |
| ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
| Not Available | Not Available | Not Available | Not Available | Not Available |
|
| ADRs Induced by Drug |
|
| ADR Term |
ADReCS ID |
ADR Frequency (FAERS)
|
ADR Severity Grade (FAERS)
|
ADR Severity Grade (CTCAE)
|
| Skin sensitisation | 23.03.03.052; 10.02.01.038 | - | - | Not Available |
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