Pharmaceutical Information |
Drug Name |
Propranolol |
Drug ID |
BADD_D01867 |
Description |
Propranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times the binding affinity for beta adrenergic receptors.[L6904] Propranolol is used to treat a number of conditions but most commonly is used for hypertension.[L6901,L6904,L6907]
Propranolol was granted FDA approval on 13 November 1967.[L6904] |
Indications and Usage |
Propranolol is indicated to treat hypertension.[L6907,L6904] Propranolol is also indicated to treat angina pectoris due to coronary atherosclerosis, atrial fibrillation, myocardial infarction, migraine, essential tremor, hypertrophic subaortic stenosis, pheochromocytoma, and proliferating infantile hemangioma.[L6904,L6907] |
Marketing Status |
approved; investigational |
ATC Code |
C07AA05 |
DrugBank ID |
DB00571
|
KEGG ID |
D08443
|
MeSH ID |
D011433
|
PubChem ID |
4946
|
TTD Drug ID |
D04JEE
|
NDC Product Code |
Not Available |
UNII |
9Y8NXQ24VQ
|
Synonyms |
Propranolol | Propanolol | Inderal | Avlocardyl | AY-20694 | AY 20694 | AY20694 | Rexigen | Dexpropranolol | Dociton | Obsidan | Obzidan | Propranolol Hydrochloride | Hydrochloride, Propranolol | Anaprilin | Anapriline | Betadren |
|
Chemical Information |
Molecular Formula |
C16H21NO2 |
CAS Registry Number |
525-66-6 |
SMILES |
CC(C)NCC(COC1=CC=CC2=CC=CC=C21)O |
Chemical Structure |
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ADRs Induced by Drug |
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*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
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ADR Term |
ADReCS ID |
ADR Frequency (FAERS)
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ADR Severity Grade (FAERS)
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ADR Severity Grade (CTCAE)
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