| Drug Name |
Progesterone |
| Drug ID |
BADD_D01852 |
| Description |
Progesterone is a hormone that occurs naturally in females, and is essential for endometrial receptivity, embryo implantation, and the successful establishment of pregnancy. A low progesterone concentration or an insufficient response to progesterone can cause infertility and pregnancy loss [A175609]. Progesterone is used in various contraceptive preparations to prevent ovulation and fertilization [T481], [A175612] as well as in other formulations to promote and support pregnancy. Please see [Medroxyprogesterone acetate], [Megestrol acetate], [Dydrogesterone] and [Hydroxyprogesterone] entries for information on various other forms of progesterone.
Pharmaceutical progesterone is made from a plant source as a starting material and is chemically identical to progesterone of human ovarian origin [FDA label]. Progesterone is available in gelatinized capsule form, vaginal gel form, tablet form, vaginal insert form, and injection form, all used for various purposes [Label,F3898,F3904,F3901,F3907]. |
| Indications and Usage |
For progesterone supplementation or replacement as part of an Assisted Reproductive Technology (ART) treatment for infertile women with progesterone deficiency and for the treatment of secondary amenorrhea. Also used for the reduction of the incidence of endometrial hyperplasia and the attendant risk of endometrial carcinoma in postmenopausal women receiving estrogen replacement therapy, as well as treatment of abnormal uterine bleeding due to hormonal imbalance in the absence of organic pathology such as fibroids or uterine cancer. |
| Marketing Status |
Prescription; Discontinued |
| ATC Code |
G03DA04 |
| DrugBank ID |
DB00396
|
| KEGG ID |
D00066
|
| MeSH ID |
D011374
|
| PubChem ID |
5994
|
| TTD Drug ID |
D07BSQ
|
| NDC Product Code |
72189-217; 17478-766; 60722-3010; 51508-002; 51552-0006; 69543-373; 0009-0078; 70518-2560; 59651-153; 75882-923; 73309-164; 79572-029; 69543-375; 76420-070; 0009-5023; 71335-0835; 70700-286; 76420-058; 44911-0047; 69452-234; 64025-9801; 71335-0825; 12875-9937; 70518-3286; 43598-349; 38779-2309; 0023-6151; 59651-152; 11014-0425; 43742-0851; 50090-2527; 82393-102; 51508-007; 11014-0051; 38779-3169; 70934-914; 11014-0042; 65162-808; 51552-1279; 82653-004; 49452-6080; 38779-0043; 51552-1248; 60870-0248; 43598-350; 76420-059; 69452-149; 0009-0105; 71092-9974; 76420-072; 43742-1375; 51552-1066; 71205-903; 51552-0738; 62991-1124; 52671-012; 48087-0057; 76420-073; 60429-868; 71335-1990; 49452-6061; 65162-807; 55150-306; 0802-8063; 0143-9725; 71335-1913; 60687-611; 63323-261; 63629-8530; 72189-204; 82653-003; 52671-011; 69543-374; 0009-0052; 63629-7475; 50090-5928; 76420-682; 70518-3392; 43857-0120; 43647-134; 10888-8109; 77382-0050; 17478-767; 73377-048; 38779-0310; 49452-6079; 46144-101; 69543-372; 12875-9242; 38779-0057; 43857-0103; 51552-0829; 82018-0012; 16637-0030; 71335-1430; 68981-005; 38779-3247; 0591-3128; 63275-9921; 11014-0189; 43857-0084; 70700-162; 60592-607; 51927-5124; 16637-0040; 10888-8110; 63083-1538; 11014-0039; 11014-0043; 76420-071; 48087-0105; 16714-158; 38779-2708; 71205-293; 55566-6500; 51927-0009; 50090-3240; 69452-233; 0009-0081; 50090-4656; 51927-1046; 60429-869; 76420-683; 82018-0014; 16714-157; 51927-9017; 22552-0049; 71335-1432; 71335-1406; 69452-148; 70700-163; 55714-9004; 53002-1760; 77382-0030; 71335-1443; 71205-902; 0009-5620; 82018-0011; 0023-6150 |
| Synonyms |
Progesterone | Pregnenedione | Progesterone, (17 alpha)-Isomer | Progesterone, (9 beta,10 alpha)-Isomer | Progesterone, (13 alpha,17 alpha)-(+-)-Isomer |
