Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Procyclidine hydrochloride
Drug ID BADD_D01851
Description A muscarinic antagonist that crosses the blood-brain barrier and is used in the treatment of drug-induced extrapyramidal disorders and in parkinsonism.
Indications and Usage For the treatment of all forms of Parkinson's Disease, as well as control of extrapyramidal reactions induced by antipsychotic agents.
Marketing Status Discontinued
ATC Code N04AA04
DrugBank ID DB00387
KEGG ID D00782
MeSH ID D011352
PubChem ID 207837
TTD Drug ID D0R1WR
NDC Product Code 17337-0090
Synonyms Procyclidine | Tricyclamol | Procyclidine Hydrochloride | Hydrochloride, Procyclidine | Kemadren | Mucinil | Procyclid | Kemadrin | Osnervan | Arpicolin
Chemical Information
Molecular Formula C19H30ClNO
CAS Registry Number 30953-82-3
SMILES C1CCC(CC1)C(CCN2CCCC2)(C3=CC=CC=C3)O.Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Constipation07.02.02.001--
Dizziness17.02.05.003; 02.01.02.004; 24.06.02.007--
Dry mouth07.06.01.002--
Dyspepsia07.01.02.001--
Muscular weakness17.05.03.005; 15.05.06.001--
Mydriasis17.02.11.003; 06.05.03.004--Not Available
Nausea07.01.07.001--
Parotitis11.01.04.001; 07.06.04.001--Not Available
Rash23.03.13.001--Not Available
Vision blurred17.17.01.010; 06.02.06.007--
Vomiting07.01.07.003--
The 1th Page    1    Total 1 Pages