Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Prilocaine hydrochloride
Drug ID BADD_D01837
Description A local anesthetic that is similar pharmacologically to lidocaine. Currently, it is used most often for infiltration anesthesia in dentistry. (From AMA Drug Evaluations Annual, 1992, p165)
Indications and Usage Used as a local anaesthetic and is often used in dentistry.
Marketing Status Prescription; Discontinued
ATC Code N01BB04
DrugBank ID DB00750
KEGG ID D01243
MeSH ID D011318
PubChem ID 92163
TTD Drug ID D06LYG
NDC Product Code 51927-0210; 62991-1693; 53335-0002; 38779-0155; 59014-5000; 79572-028; 66312-630; 51552-1535; 49452-6010; 82481-016; 52119-016; 59014-0051; 51927-0101; 17381-249
Synonyms Prilocaine | Propitocaine | Citanest Octapressin | Xylonest | Citanest | Prilocaine Hydrochloride
Chemical Information
Molecular Formula C13H21ClN2O
CAS Registry Number 1786-81-8
SMILES CCCNC(C)C(=O)NC1=CC=CC=C1C.Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Anaphylactoid reaction10.01.07.003; 24.06.03.007--Not Available
Anxiety19.06.02.002--
Cardiac arrest02.03.04.001--
Confusional state19.13.01.001; 17.02.03.005--
Diplopia17.17.01.005; 06.02.06.002--Not Available
Dizziness02.01.02.004; 24.06.02.007; 17.02.05.003--
Euphoric mood19.04.02.006--
Feeling cold08.01.09.008--Not Available
Feeling hot08.01.09.009--Not Available
Hypoaesthesia17.02.06.023--Not Available
Loss of consciousness17.02.04.004--Not Available
Muscle twitching15.05.03.005--Not Available
Nervousness19.06.02.003--Not Available
Oedema14.05.06.010; 08.01.07.006--Not Available
Respiratory depression22.02.01.010; 17.02.05.047--Not Available
Seizure17.12.03.001--
Skin lesion23.03.03.010--Not Available
Somnolence17.02.04.006; 19.02.05.003--
Swelling08.01.03.015--Not Available
Tinnitus17.04.07.004; 04.04.01.002--
Tremor17.01.06.002--
Urticaria23.04.02.001; 10.01.06.001--
Vision blurred17.17.01.010; 06.02.06.007--
Vomiting07.01.07.003--
Paraesthesia oral17.02.06.008; 07.05.03.003--Not Available
Neurological symptom17.02.05.010--Not Available
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