Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Prilocaine
Drug ID BADD_D01836
Description A local anesthetic that is similar pharmacologically to lidocaine. Currently, it is used most often for infiltration anesthesia in dentistry. (From AMA Drug Evaluations Annual, 1992, p165)
Indications and Usage Used as a local anaesthetic and is often used in dentistry.
Marketing Status Prescription; Discontinued
ATC Code N01BB04
DrugBank ID DB00750
KEGG ID D00553
MeSH ID D011318
PubChem ID 4906
TTD Drug ID D06LYG
NDC Product Code 17381-017; 22365-119; 73309-214; 24196-186; 49452-6011; 53335-0004; 59014-0052; 69617-011
Synonyms Prilocaine | Propitocaine | Citanest Octapressin | Xylonest | Citanest | Prilocaine Hydrochloride
Chemical Information
Molecular Formula C13H20N2O
CAS Registry Number 721-50-6
SMILES CCCNC(C)C(=O)NC1=CC=CC=C1C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Vision blurred17.17.01.010; 06.02.06.007--
Vomiting07.01.07.003--
Nerve injury12.01.12.002; 17.02.10.007--Not Available
Carotid pulse13.14.04.011--Not Available
Hypoaesthesia oral17.02.06.021; 07.05.05.003--Not Available
Paraesthesia oral07.05.03.003; 17.02.06.008--Not Available
Neurological symptom17.02.05.010--Not Available
Pulmonary function test decreased13.19.01.001--Not Available
Arterial occlusive disease24.04.02.021--Not Available
Myocardial depression02.04.02.015--Not Available
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