Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Prednisolone acetate
Drug ID BADD_D01832
Description Prednisolone acetate is a [prednisolone] molecule bound to an acetate functional group by an ester bond.[L9449] Prednisolone acetate was granted FDA approval in 1955.[L9449]
Indications and Usage For the treatment of primary or secondary adrenocortical insufficiency, such as congenital adrenal hyperplasia, thyroiditis. Also used to treat psoriatic arthritis, rheumatoid arthritis, ankylosing spondylitis, bursitis, acute gouty arthritis and epicondylitis. Also indicated for treatment of systemic lupus erythematosus, pemphigus and acute rhematic carditis. Can be used in the treatment of leukemias, lymphomas, thrombocytopenia purpura and autoimmune hemolytic anemia. Can be used to treat celiac disease, insulin resistance, ulcerative colitis and liver disorders.
Marketing Status Prescription; Discontinued
ATC Code A07EA01; C05AA04; D07AA03; D07XA02; H02AB06; R01AD02; S01BA04; S01CB02; S02BA03; S03BA02
DrugBank ID DB15566
KEGG ID D00980
MeSH ID C009935
PubChem ID 5834
TTD Drug ID Not Available
NDC Product Code 62991-1692; 82298-108; 22552-0044; 52128-150; 46439-8761; 11980-180; 11980-174; 50396-7014; 64958-0048; 50090-0561; 38779-0152; 51552-0027; 61314-637; 60722-3006; 60722-2005; 76420-204; 49452-5990; 50090-5275; 72189-055; 68071-2222; 82298-107; 60758-119; 51672-1338; 50090-1912; 50090-0559
Synonyms prednisolone acetate | prednisolone 21-acetate | pred forte | Scherisolone-Kristall suspension
Chemical Information
Molecular Formula C23H30O6
CAS Registry Number 52-21-1
SMILES CC(=O)OCC(=O)C1(CCC2C1(CC(C3C2CCC4=CC(=O)C=CC34C)O)C)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Osteoporosis15.02.03.002; 14.04.04.002--
Pain08.01.08.004--
Pancreatitis07.18.01.001--
Papilloedema17.07.02.004; 06.09.02.002; 24.03.07.001--
Paraesthesia17.02.06.005--
Paraparesis17.01.04.006--Not Available
Paraplegia17.01.04.007--Not Available
Pathological fracture16.32.03.007; 15.08.02.008; 12.04.02.006--Not Available
Peptic ulcer07.04.07.001--Not Available
Personality change19.05.01.006; 17.02.05.019--
Petechiae24.07.06.004; 23.06.01.003; 01.01.03.002--Not Available
Photophobia17.17.02.006; 06.01.01.0040.012554%
Pruritus23.03.12.001--
Pulmonary oedema22.01.03.003; 02.05.02.003--
Rash23.03.13.001--Not Available
Secondary adrenocortical insufficiency05.01.02.003; 14.11.01.014--Not Available
Seizure17.12.03.001--
Sensory disturbance17.02.07.006--Not Available
Shock24.06.02.002--Not Available
Skin atrophy23.01.05.001--
Skin hyperpigmentation23.05.01.003--
Skin hypopigmentation23.05.02.003--
Skin striae23.01.05.002--Not Available
Sodium retention14.05.04.003--Not Available
Spermatozoa abnormal13.20.01.005--Not Available
Spermatozoa progressive motility abnormal13.20.01.003--Not Available
Spinal compression fracture15.08.05.004; 14.04.04.003; 12.04.04.001--Not Available
Syncope17.02.04.008; 02.01.02.008; 24.06.02.012--
Tachycardia02.03.02.007--Not Available
Tendon rupture15.07.01.008; 12.01.07.003--Not Available
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