Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Prednisolone
Drug ID BADD_D01831
Description Prednisolone is a glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects.[A187463] Prednisolone was granted FDA approval on 21 June 1955.[L9431]
Indications and Usage Prednisolone is indicated to treat endocrine, rheumatic, and hematologic disorders; collagen, dermatologic, ophthalmic, respiratory, and gastrointestinal diseases; allergic and edematous states; and other conditions like tuberculous meningitis.[L9542]
Marketing Status approved; vet_approved
ATC Code A01AC04; A07EA01; C05AA04; D07AA03; D07XA02; H02AB06; R01AD02; S01BA04; S01CB02; S02BA03; S03BA02
DrugBank ID DB00860
KEGG ID D00472
MeSH ID D011239
PubChem ID 5755
TTD Drug ID D0D1SG
NDC Product Code 38779-0150; 64958-0097; 82298-104; 67296-1656; 50383-042; 59651-491; 63187-466; 0527-5406; 65089-0038; 50090-0655; 57582-004; 62135-437; 73534-505; 49452-5980; 82298-105; 82298-106; 60592-911; 60722-3001; 51927-0234; 22552-0052
UNII 9PHQ9Y1OLM
Synonyms Prednisolone | Predate | Predonine | Di-Adreson-F | Di Adreson F | DiAdresonF
Chemical Information
Molecular Formula C21H28O5
CAS Registry Number 50-24-8
SMILES CC12CC(C3C(C1CCC2(C(=O)CO)O)CCC4=CC(=O)C=CC34C)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Dysbiosis12.02.05.053; 07.11.01.0340.000035%Not Available
Epstein Barr virus positive mucocutaneous ulcer07.05.06.010; 01.13.02.006; 23.07.03.024; 16.21.02.006; 11.05.10.0090.000052%Not Available
Gallbladder rupture12.01.17.005; 09.03.02.0120.000052%Not Available
Gastric pneumatosis07.11.01.0360.000035%Not Available
Giant cell arteritis24.12.02.003; 17.08.02.033; 10.02.02.032; 06.07.02.0100.000035%Not Available
Growth failure14.03.02.030; 05.03.02.006; 15.03.05.0150.000070%Not Available
Haematoma muscle24.07.01.091; 15.05.03.036; 12.01.07.0150.000035%Not Available
Haemophagocytic lymphohistiocytosis16.32.03.038; 10.02.01.077; 01.05.01.0260.000297%Not Available
Histiocytic necrotising lymphadenitis16.21.02.007; 01.13.02.0070.000035%Not Available
Hyperglycaemic hyperosmolar nonketotic syndrome17.02.04.022; 14.07.04.009; 05.07.04.0090.000087%Not Available
Hypersensitivity pneumonitis22.01.01.027; 10.01.03.0560.000070%Not Available
Idiopathic intracranial hypertension17.07.02.011--Not Available
Immune thrombocytopenia10.02.01.083; 01.08.01.0130.000175%Not Available
Immune-mediated myositis15.05.01.012; 10.02.01.0880.000070%Not Available
Immunoglobulin G4 related disease10.04.04.028; 15.06.01.0200.000052%Not Available
Intestinal mucosal hypertrophy07.11.01.0400.000035%Not Available
Intra-abdominal fluid collection21.07.04.014; 07.07.01.0140.000052%Not Available
Joint noise15.01.02.0120.000035%Not Available
Left ventricular enlargement02.04.02.0450.000035%Not Available
Lung opacity22.12.01.0060.000035%Not Available
Lung squamous cell carcinoma stage I22.08.01.028; 16.19.01.0130.000035%Not Available
Lung transplant rejection12.02.07.015; 10.02.03.011; 22.01.01.0290.000035%Not Available
Lupus endocarditis15.06.02.014; 10.04.03.014; 02.09.01.0040.000035%Not Available
Lupus pancreatitis07.18.01.012; 15.06.02.016; 10.04.03.0160.000070%Not Available
Malacoplakia vesicae20.03.02.013; 11.07.01.024; 10.03.02.0090.000035%Not Available
Meningitis eosinophilic17.06.03.005; 01.02.04.0240.000035%Not Available
Mikulicz's disease07.06.03.004; 06.08.02.0120.000035%Not Available
Monoclonal B-cell lymphocytosis01.02.01.0190.000070%Not Available
Neovascular age-related macular degeneration06.09.03.0330.000035%Not Available
Neuropsychiatric lupus19.07.03.008; 17.02.10.008; 15.06.02.008; 10.04.03.0080.000035%Not Available
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ADReCS-Target
Drug Name ADR Term Target
Tip:  Drug Name  ADR Term  Protein  Variation  Gene