Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Prednisolone
Drug ID BADD_D01831
Description Prednisolone is a glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects.[A187463] Prednisolone was granted FDA approval on 21 June 1955.[L9431]
Indications and Usage Prednisolone is indicated to treat endocrine, rheumatic, and hematologic disorders; collagen, dermatologic, ophthalmic, respiratory, and gastrointestinal diseases; allergic and edematous states; and other conditions like tuberculous meningitis.[L9542]
Marketing Status approved; vet_approved
ATC Code A01AC04; A07EA01; C05AA04; D07AA03; D07XA02; H02AB06; R01AD02; S01BA04; S01CB02; S02BA03; S03BA02
DrugBank ID DB00860
KEGG ID D00472
MeSH ID D011239
PubChem ID 5755
TTD Drug ID D0D1SG
NDC Product Code 38779-0150; 64958-0097; 82298-104; 67296-1656; 50383-042; 59651-491; 63187-466; 0527-5406; 65089-0038; 50090-0655; 57582-004; 62135-437; 73534-505; 49452-5980; 82298-105; 82298-106; 60592-911; 60722-3001; 51927-0234; 22552-0052
UNII 9PHQ9Y1OLM
Synonyms Prednisolone | Predate | Predonine | Di-Adreson-F | Di Adreson F | DiAdresonF
Chemical Information
Molecular Formula C21H28O5
CAS Registry Number 50-24-8
SMILES CC12CC(C3C(C1CCC2(C(=O)CO)O)CCC4=CC(=O)C=CC34C)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Mononeuropathy multiplex17.09.02.0120.000035%Not Available
Muscle hypertrophy15.05.03.0300.000035%Not Available
Myocardial fibrosis02.04.02.0160.000035%Not Available
Neonatal respiratory distress syndrome22.11.02.010; 18.04.10.0030.000035%Not Available
Non-alcoholic fatty liver14.08.04.023; 09.01.07.0340.000052%Not Available
Normal newborn18.08.06.0010.000140%Not Available
Overweight14.03.02.0210.000035%Not Available
Peripheral T-cell lymphoma unspecified16.17.06.001; 01.11.06.0010.000052%Not Available
Persecutory delusion19.10.01.0070.000122%Not Available
Placenta praevia18.05.02.0040.000035%Not Available
Polychromasia01.07.02.0130.000035%Not Available
Pouchitis12.02.03.022; 07.08.03.0170.000384%Not Available
Pulmonary artery stenosis22.06.03.006; 24.04.09.0110.000035%Not Available
Pupil fixed17.02.11.008; 06.05.03.0120.000035%Not Available
Rectal perforation07.04.01.0040.000087%
Rectal stenosis07.13.05.0030.000035%
Retinal pigment epitheliopathy06.09.03.0240.000087%Not Available
Small for dates baby18.04.02.0020.000122%Not Available
Symptom masked08.01.03.0780.000332%Not Available
Takayasu's arteritis24.12.02.008; 10.02.02.0280.000035%Not Available
Thrombocytopenia neonatal18.04.03.005; 01.08.01.0100.000087%Not Available
Toxic nodular goitre14.11.01.047; 05.02.02.0070.000035%Not Available
Ureteric stenosis20.06.01.0100.000035%Not Available
Vulval cancer21.08.03.005; 16.12.08.0010.000035%Not Available
Aneurysm ruptured24.02.01.0020.000035%Not Available
Rheumatoid vasculitis24.12.04.022; 15.01.03.006; 10.04.06.0080.000035%Not Available
Concomitant disease progression08.01.03.0640.000052%Not Available
Patellofemoral pain syndrome15.01.08.0130.000035%Not Available
Neonatal hypotension18.04.07.008; 24.06.03.0140.000035%Not Available
Live birth18.08.02.0070.000318%Not Available
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ADReCS-Target
Drug Name ADR Term Target
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