Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Prednisolone
Drug ID BADD_D01831
Description Prednisolone is a glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects.[A187463] Prednisolone was granted FDA approval on 21 June 1955.[L9431]
Indications and Usage Prednisolone is indicated to treat endocrine, rheumatic, and hematologic disorders; collagen, dermatologic, ophthalmic, respiratory, and gastrointestinal diseases; allergic and edematous states; and other conditions like tuberculous meningitis.[L9542]
Marketing Status approved; vet_approved
ATC Code A01AC04; A07EA01; C05AA04; D07AA03; D07XA02; H02AB06; R01AD02; S01BA04; S01CB02; S02BA03; S03BA02
DrugBank ID DB00860
KEGG ID D00472
MeSH ID D011239
PubChem ID 5755
TTD Drug ID D0D1SG
NDC Product Code 38779-0150; 64958-0097; 82298-104; 67296-1656; 50383-042; 59651-491; 63187-466; 0527-5406; 65089-0038; 50090-0655; 57582-004; 62135-437; 73534-505; 49452-5980; 82298-105; 82298-106; 60592-911; 60722-3001; 51927-0234; 22552-0052
UNII 9PHQ9Y1OLM
Synonyms Prednisolone | Predate | Predonine | Di-Adreson-F | Di Adreson F | DiAdresonF
Chemical Information
Molecular Formula C21H28O5
CAS Registry Number 50-24-8
SMILES CC12CC(C3C(C1CCC2(C(=O)CO)O)CCC4=CC(=O)C=CC34C)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Skin hyperpigmentation23.05.01.0030.000035%
Skin lesion23.03.03.0100.000175%Not Available
Skin necrosis23.03.03.0110.000122%Not Available
Skin odour abnormal23.03.03.0120.000070%
Skin papilloma23.10.01.002; 16.26.01.002; 11.05.07.0010.000052%
Skin reaction23.03.03.013; 10.01.03.0190.000070%Not Available
Skin striae23.01.05.0020.000070%Not Available
Skin ulcer24.04.03.007; 23.07.03.0030.000357%
Sleep disorder19.02.04.0010.000332%Not Available
Small intestinal perforation07.04.06.0060.000122%
Sodium retention14.05.04.003--Not Available
Speech disorder22.12.03.027; 19.19.02.002; 17.02.08.0030.000245%Not Available
Spinal compression fracture15.08.05.004; 12.04.04.001; 14.04.04.003--Not Available
Spinal cord compression17.10.01.0060.000035%
Spinal osteoarthritis15.01.04.0030.000052%Not Available
Splenic infarction24.04.08.024; 01.09.02.0040.000052%Not Available
Splenomegaly01.09.02.0010.000087%Not Available
Sputum discoloured22.02.03.0100.000035%Not Available
Squamous cell carcinoma16.16.01.0020.000140%Not Available
Squamous cell carcinoma of skin23.08.02.005; 16.03.02.0050.000070%Not Available
Steroid withdrawal syndrome19.04.02.014; 08.06.02.013; 05.01.02.0070.000332%Not Available
Stevens-Johnson syndrome10.01.01.045; 12.03.01.014; 11.07.01.005; 23.03.01.0070.000157%
Stillbirth18.01.02.002; 08.04.01.0060.000105%Not Available
Stress19.06.02.004--Not Available
Stress ulcer07.04.04.0070.000035%Not Available
Stridor22.04.02.0030.000052%
Subcutaneous emphysema23.07.04.006; 12.02.06.0020.000087%
Sudden death08.04.01.003; 02.03.04.0130.000087%
Superior sagittal sinus thrombosis24.01.04.004; 17.08.03.0010.000087%Not Available
Supraventricular tachycardia02.03.03.0120.000070%
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ADReCS-Target
Drug Name ADR Term Target
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