Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Pomalidomide
Drug ID BADD_D01798
Description Pomalidomide, an analogue of thalidomide, is an immunomodulatory antineoplastic agent. FDA approved on February 8, 2013.
Indications and Usage Pomalidomide is indicated for patients with multiple myeloma who have received at least two prior therapies including lenalidomide and bortezomib and have demonstrated disease progression on or within 60 days of completion of the last therapy.
Marketing Status approved
ATC Code L04AX06
DrugBank ID DB08910
KEGG ID D08976
MeSH ID C467566
PubChem ID 134780
TTD Drug ID D0A3ZU
NDC Product Code 65015-893; 17337-0068; 63069-404; 68554-0092; 70225-1106; 59572-501; 59572-502; 55111-989; 68554-0091; 82245-0108; 63069-402; 42973-232; 54893-0038; 59572-503; 59572-504; 63069-403
UNII D2UX06XLB5
Synonyms pomalidomide | CC-4047 | CC 4047 | CC4047 | Imnovid | Pomalyst | actimid
Chemical Information
Molecular Formula C13H11N3O4
CAS Registry Number 19171-19-8
SMILES C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Tongue blistering07.14.02.0140.000820%Not Available
Tongue discolouration07.14.02.0060.001061%Not Available
Tongue disorder07.14.01.0020.001471%Not Available
Tongue ulceration07.14.01.0030.001760%Not Available
Tooth disorder07.09.05.0010.036842%Not Available
Tooth loss12.01.17.026; 07.09.09.0010.002700%Not Available
Toothache07.09.06.0010.005401%
Tremor17.01.06.0020.080845%
Trichorrhexis23.02.06.0070.001640%Not Available
Trismus17.01.03.004; 15.05.04.0040.001471%
Tumour lysis syndrome16.32.03.002; 14.05.01.004--
Tunnel vision17.17.01.013; 06.02.07.0050.000241%Not Available
Tympanic membrane perforation12.01.14.001; 04.05.04.0010.000241%Not Available
Unresponsive to stimuli17.02.05.031--Not Available
Upper respiratory tract infection22.07.03.011; 11.01.13.009--
Urethral disorder20.07.01.002--Not Available
Urinary retention20.02.02.011--
Urinary tract disorder20.08.01.001--Not Available
Urinary tract infection20.08.02.001; 11.01.14.004--
Urine abnormality20.02.01.0130.001230%Not Available
Urticaria23.04.02.001; 10.01.06.001--
Uterine disorder21.07.01.0060.000603%Not Available
Vein disorder24.03.02.0150.000651%Not Available
Vertigo04.04.01.003; 17.02.12.002--
Viral infection11.05.04.001--Not Available
Vision blurred17.17.01.010; 06.02.06.0070.045377%
Vomiting07.01.07.003--
Weight decreased13.15.01.005--
Weight increased13.15.01.006--
White blood cell count decreased13.01.06.012--
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