Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Podophyllum resin
Drug ID BADD_D01791
Description Podophyllin is a resin extracted from the roots of _Podophyllum peltatum_ (American mandrake) and _Podophyllum emodi_, which contains numerous compounds, amongst which is podophyllin (as well as the drug [podophyllotoxin]). Podophyllin is the principal active component. Podophyllin arrests mitosis in metaphase.
Indications and Usage 25% podophyllin (in benzoin tincture) is indicated for the removal of soft genital (venereal) warts (condylomata acuminata).
Marketing Status Not Available
ATC Code Not Available
DrugBank ID DB09094
KEGG ID D06484
MeSH ID D011033
PubChem ID 11979494
TTD Drug ID Not Available
NDC Product Code 49452-5480; 81867-0574; 63629-8699; 63570-008; 0574-0601; 51552-0016
Synonyms Podophyllin | Podophyllum Resin | Resin, Podophyllum
Chemical Information
Molecular Formula C88H92O34
CAS Registry Number 9000-55-9
SMILES COC1=CC(=CC(=C1OC)OC)C2C3C(COC3=O)C(C4=CC5=C(C=C24)OCO5)O.COC1=CC(=CC(=C1OC)OC)C 2C3C(COC3=O)C(C4=CC5=C(C=C24)OCO5)O.COC1=CC(=CC(=C1OC)OC)C2C(C(C(C3=CC4=C(C=C23) OCO4)O)CO)C(=O)O.COC1=CC(=CC(=C1OC)OC)C2C(C(C(C3=CC4=C(C=C23)OCO4)O)CO)C(=O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Coma17.02.09.001--Not Available
Congenital anomaly03.02.01.001--Not Available
Death08.04.01.001--
Ileus paralytic07.02.05.001--Not Available
Leukopenia01.02.02.001--Not Available
Paraesthesia17.02.06.005--
Polyneuropathy17.09.03.012--Not Available
Pyrexia08.05.02.003--
Stillbirth18.01.02.002; 08.04.01.006--Not Available
Thrombocytopenia01.08.01.002--Not Available
Foetal death18.01.02.003; 08.04.01.011--
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