Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Piroxicam
Drug ID BADD_D01784
Description A cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. Its long half-life enables it to be administered once daily.
Indications and Usage For treatment of osteoarthritis and rheumatoid arthritis.
Marketing Status Prescription; Discontinued
ATC Code M01AC01; M02AA07; S01BC06
DrugBank ID DB00554
KEGG ID D00127
MeSH ID D010894
PubChem ID 54676228
TTD Drug ID D00IBN
NDC Product Code 22365-114; 59762-0145; 53747-044; 72789-210; 0395-8163; 0143-3107; 0069-3220; 59762-0140; 59348-0014; 46438-0053; 68981-041; 71205-032; 0069-3230; 60592-604; 17337-0538; 60715-3270; 29300-255; 0143-3108; 61919-193; 29300-256; 51927-0145; 29033-012; 46438-0639; 64380-842; 38779-0302; 0093-0756; 42543-115; 72789-211; 42571-176; 42571-177; 49452-5476; 42291-677; 70771-1430; 42291-674; 29033-013; 50090-4779; 51927-1699; 70771-1429; 0093-0757; 63629-9150; 62991-1113; 55700-697; 64380-843; 71335-1999; 63629-9148; 63629-9149; 71205-203; 42543-114; 61919-188; 63187-972
Synonyms Piroxicam | CP-16171 | CP 16171 | CP16171 | Feldene
Chemical Information
Molecular Formula C15H13N3O4S
CAS Registry Number 36322-90-4
SMILES CN1C(=C(C2=CC=CC=C2S1(=O)=O)O)C(=O)NC3=CC=CC=N3
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Hepatic function abnormalGlycogen [starch] synthase, muscleP13807Not Available1338186; 7733654; 6416813; 6766890; 237970; 7575414; 3105560; 6096366
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Chest pain22.02.08.003; 08.01.08.002; 02.02.02.0110.004300%Not Available
Chills15.05.03.016; 08.01.09.001--
Cholestasis09.01.01.0010.008600%Not Available
Colitis07.08.01.0010.004300%
Coma17.02.09.0010.004300%Not Available
Confusional state19.13.01.001; 17.02.03.005--
Conjunctivitis11.01.06.012; 06.04.01.002--
Constipation07.02.02.001--
Cystitis20.03.02.002; 11.01.14.001--
Deafness04.02.01.001--Not Available
Death08.04.01.001--
Depression19.15.01.001--
Dermatitis23.03.04.002--Not Available
Dermatitis bullous23.03.01.0020.004300%
Dermatitis contact23.03.04.004; 12.03.01.040; 10.01.01.003--Not Available
Dermatitis exfoliative23.03.07.001; 10.01.01.004--
Diarrhoea07.02.01.001--
Dilatation ventricular02.04.02.0260.004300%Not Available
Discomfort08.01.08.003--Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.0040.015050%
Drug abuse19.07.02.0100.001122%Not Available
Drug hypersensitivity10.01.01.0010.225755%Not Available
Dry mouth07.06.01.002--
Duodenal ulcer07.04.02.002--
Dyspepsia07.01.02.0010.004300%
Dysphagia07.01.06.0030.001122%
Dyspnoea22.02.01.004; 02.01.03.0020.015050%
Dysuria20.02.02.002--
Ecchymosis24.07.06.002; 23.06.01.001; 01.01.03.001--Not Available
Eczema23.03.04.006--
The 2th Page    First    Pre   2 3 4 5 6    Next   Last    Total 8 Pages