Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Pindolol
Drug ID BADD_D01776
Description Pindolol is a first generation non-selective beta blocker used in the treatment of hypertension.[L32353] Early research into the use of pindolol found it had chronotropic effects, and so further investigation focused on the treatment of arrhythmia.[A231059] Research into pindolol's use in the treatment of hypertension began in the early 1970s.[A231064] Pindolol was granted FDA approval on 3 September 1982.[L32348]
Indications and Usage For the management of hypertension, edema, ventricular tachycardias, and atrial fibrillation.
Marketing Status Prescription; Discontinued
ATC Code C07AA03
DrugBank ID DB00960
KEGG ID D00513
MeSH ID D010869
PubChem ID 4828
TTD Drug ID D0F2PO
NDC Product Code 64330-109; 49169-0006; 29033-029; 57664-656; 29033-028; 0378-0127; 62559-560; 72789-100; 70771-1134; 62559-561; 70771-1135; 76385-131; 70710-1064; 72789-099; 70710-1063; 76385-132; 57664-655; 0378-0052
Synonyms Pindolol | Prindolol | Visken | LB-46 | LB 46 | LB46
Chemical Information
Molecular Formula C14H20N2O2
CAS Registry Number 13523-86-9
SMILES CC(C)NCC(COC1=CC=CC2=C1C=CN2)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Somnolence19.02.05.003; 17.02.04.006--
Syncope24.06.02.012; 17.02.04.008; 02.01.02.008--
Tachycardia02.03.02.007--Not Available
Tension19.06.02.005--Not Available
Tinnitus17.04.07.004; 04.04.01.002--
Tremor17.01.06.002--
Vertigo04.04.01.003; 17.02.12.002--
Visual impairment06.02.06.008--Not Available
Vomiting07.01.07.003--
Weight increased13.15.01.006--
Wheezing22.03.01.009--
Musculoskeletal disorder15.03.01.004--Not Available
Ocular discomfort06.08.03.008--Not Available
Coronary artery insufficiency24.04.04.016; 02.02.01.008--Not Available
Musculoskeletal discomfort15.03.04.001--Not Available
Transaminases increased13.03.01.015--Not Available
Dermatitis psoriasiform23.03.14.004--Not Available
Angiopathy24.03.02.007--Not Available
Hot flush08.01.03.027; 24.03.01.005; 21.02.02.001--
Cardiac disorder02.01.01.003--Not Available
Mediastinal disorder22.09.03.001--Not Available
Mental disorder19.07.01.002--Not Available
Erectile dysfunction21.03.01.007; 19.08.04.001--
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