| Pharmaceutical Information |
| Drug Name |
Pimozide |
| Drug ID |
BADD_D01774 |
| Description |
A diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to haloperidol for the suppression of vocal and motor tics in patients with Tourette syndrome. Although the precise mechanism of action is unknown, blockade of postsynaptic dopamine receptors has been postulated. (From AMA Drug Evaluations Annual, 1994, p403) |
| Indications and Usage |
Used for the suppression of motor and phonic tics in patients with Tourette's Disorder who have failed to respond satisfactorily to standard treatment. |
| Marketing Status |
Prescription |
| ATC Code |
N05AG02 |
| DrugBank ID |
DB01100
|
| KEGG ID |
D00560
|
| MeSH ID |
D010868
|
| PubChem ID |
16362
|
| TTD Drug ID |
D00KHM
|
| NDC Product Code |
66577-017; 49884-347; 76438-002; 49884-348; 14474-029 |
| Synonyms |
Pimozide | Antalon | Orap | Orap forte | R-6238 | R6238 |
|
| Chemical Information |
| Molecular Formula |
C28H29F2N3O |
| CAS Registry Number |
2062-78-4 |
| SMILES |
C1CN(CCC1N2C3=CC=CC=C3NC2=O)CCCC(C4=CC=C(C=C4)F)C5=CC=C(C=C5)F |
| Chemical Structure |
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| ADR Related Proteins Induced by Drug |
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| ADRs Induced by Drug |
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| ADR Term |
ADReCS ID |
ADR Frequency (FAERS)
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ADR Severity Grade (FAERS)
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ADR Severity Grade (CTCAE)
|
| Anal incontinence | 17.05.01.021; 07.01.06.029 | - | - | |
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