Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Pimecrolimus
Drug ID BADD_D01773
Description Pimecrolimus is an immunomodulating agent that was first marketed by Novartis under the trade name Elidel. It is now promoted in Canada by Galderma since early 2007. It is currently available as a topic cream used in the treatment of atopic dermatitis (eczema).
Indications and Usage For treatment of mild to moderate atopic dermatitis.
Marketing Status Prescription
ATC Code D11AH02
DrugBank ID DB00337
KEGG ID D05480
MeSH ID C117268
PubChem ID 6447131
TTD Drug ID D0Z4UN
NDC Product Code 70518-2292; 0591-2944; 62227-004; 16436-0115; 68682-111; 55486-1585; 72969-058; 65727-045; 68682-110; 53296-0115; 0187-5103; 68254-0014; 68462-609; 0187-5100; 68682-112; 0187-5101; 0187-5102
Synonyms pimecrolimus | 33-epi-chloro-33-desoxyascomycin | SDZ ASM 981 | SDZ-ASM-981 | ASM 981 | Elidel
Chemical Information
Molecular Formula C43H68ClNO11
CAS Registry Number 137071-32-0
SMILES CCC1C=C(CC(CC(C2C(CC(C(O2)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C(CC1=O)O)C)C(=CC4CCC(C(C 4)OC)Cl)C)O)C)OC)OC)C)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Skin papilloma23.10.01.002; 16.26.01.002; 11.05.07.001--
Squamous cell carcinoma16.16.01.002--Not Available
Superinfection11.01.08.009--Not Available
Swelling08.01.03.015--Not Available
Tonsillitis22.07.03.008; 11.01.13.006--Not Available
Toothache07.09.06.001--
Tracheobronchitis22.07.03.010; 11.01.13.008--Not Available
Upper respiratory tract infection22.07.03.011; 11.01.13.009--
Urticaria23.04.02.001; 10.01.06.001--
Varicella23.09.03.003; 11.05.02.004--Not Available
Viral infection11.05.04.001--Not Available
Viral upper respiratory tract infection22.07.02.004; 11.05.04.007--Not Available
Vomiting07.01.07.003--
Wheezing22.03.01.009--
Musculoskeletal discomfort15.03.04.001--Not Available
Arthritis bacterial15.01.05.001; 11.02.01.004--Not Available
Staphylococcal infection11.02.05.002--Not Available
Bacterial infection11.02.01.005--Not Available
Breast disorder21.05.04.004--Not Available
Infestation23.09.05.001; 11.09.01.001--Not Available
Malnutrition14.03.02.004--Not Available
Mediastinal disorder22.09.03.001--Not Available
Inner ear disorder04.04.02.002--Not Available
Herpes dermatitis23.09.03.005; 11.05.02.011--Not Available
Application site burn23.03.11.013; 12.07.01.038; 08.02.01.038--Not Available
Oropharyngeal discomfort07.05.05.008; 22.02.05.027--Not Available
Oropharyngeal pain22.02.05.022; 07.05.05.004--
Sensitisation08.01.05.009; 10.02.01.012--Not Available
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