Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Pimecrolimus
Drug ID BADD_D01773
Description Pimecrolimus is an immunomodulating agent that was first marketed by Novartis under the trade name Elidel. It is now promoted in Canada by Galderma since early 2007. It is currently available as a topic cream used in the treatment of atopic dermatitis (eczema).
Indications and Usage For treatment of mild to moderate atopic dermatitis.
Marketing Status Prescription
ATC Code D11AH02
DrugBank ID DB00337
KEGG ID D05480
MeSH ID C117268
PubChem ID 6447131
TTD Drug ID D0Z4UN
NDC Product Code 70518-2292; 0591-2944; 62227-004; 16436-0115; 68682-111; 55486-1585; 72969-058; 65727-045; 68682-110; 53296-0115; 0187-5103; 68254-0014; 68462-609; 0187-5100; 68682-112; 0187-5101; 0187-5102
Synonyms pimecrolimus | 33-epi-chloro-33-desoxyascomycin | SDZ ASM 981 | SDZ-ASM-981 | ASM 981 | Elidel
Chemical Information
Molecular Formula C43H68ClNO11
CAS Registry Number 137071-32-0
SMILES CCC1C=C(CC(CC(C2C(CC(C(O2)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C(CC1=O)O)C)C(=CC4CCC(C(C 4)OC)Cl)C)O)C)OC)OC)C)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Ear disorder04.03.01.001--Not Available
Ear infection04.03.01.006; 11.01.05.001--Not Available
Ear pain04.03.01.003--
Eczema herpeticum23.03.04.026; 11.05.02.016; 10.01.04.006--Not Available
Epistaxis24.07.01.005; 22.04.03.001--
Erythema23.03.06.001--Not Available
Eye disorder06.08.03.001--Not Available
Eye infection11.01.06.001; 06.04.05.007--
Eye irritation06.04.05.003--Not Available
Face oedema23.04.01.004; 10.01.05.002; 08.01.07.003--
Flushing24.03.01.002; 23.06.05.003; 08.01.03.025--
Folliculitis23.09.04.007; 11.01.12.018--
Furuncle23.09.01.004; 11.02.05.008--Not Available
Gastroenteritis11.01.07.004; 07.19.03.001--Not Available
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal pain07.01.05.005--
Headache17.14.01.001--
Herpes simplex23.09.03.001; 11.05.02.001--Not Available
Hypersensitivity10.01.03.003--
Immune system disorder10.02.01.001--Not Available
Impetigo23.09.01.006; 11.01.12.006--Not Available
Infection11.01.08.002--Not Available
Influenza22.07.02.001; 11.05.03.001--Not Available
Influenza like illness08.01.03.010--
Laceration23.03.11.004; 12.01.06.006--Not Available
Leukaemia16.01.03.001; 01.10.03.001--
Leukoderma23.05.02.001--Not Available
Lymphoma01.12.01.001; 16.20.01.001--Not Available
Malignant histiocytosis16.21.04.001; 01.13.04.001--Not Available
Malignant melanoma23.08.01.001; 16.03.01.001--Not Available
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