Drug Name |
Phentermine hydrochloride |
Drug ID |
BADD_D01757 |
Description |
Phentermine is a sympathomimetic amine anorectic agent and it was introduced in 1959 as part of an anti-obesity combination drug.[A174361, A174364] It is chemically related to amphetamine and it is commonly referred to as an atypical amphetamine.[A174370] Phentermine has not been reported an addictive potential which allows this agent to be classified under the Schedule IV drugs (low abuse potential).[A174367]
Phentermine was FDA approved for short-term weight management in 1959 and it became widely used in 1960. This initial product, formed by the combination of phentermine with [fenfluramine] and [dexfenfluramine] was discontinued after finding several reports of abnormal valves in nearly 30% of the consumers.[A174376, T403] Later on, phentermine was approved alone and in combination with topiramate in 2012 as a new alternative that required lower doses of phentermine to obtain the desired effect.[A174373] |
Indications and Usage |
For the treatment and management of obesity. |
Marketing Status |
Prescription; Discontinued |
ATC Code |
A08AA01 |
DrugBank ID |
DB00191
|
KEGG ID |
D05459
|
MeSH ID |
D010645
|
PubChem ID |
70969
|
TTD Drug ID |
D0U0RZ
|
NDC Product Code |
0527-1308; 11534-160; 63629-1041; 66022-0112; 0527-1310; 0185-5000; 71335-0564; 0527-1445; 55289-791; 50436-6744; 50090-1534; 71335-0474; 71335-1312; 68788-9271; 72789-175; 63629-1107; 72189-301; 51224-202; 68071-2640; 63629-2389; 70518-3407; 11534-159; 57844-019; 57844-140; 63629-2387; 61919-557; 68788-7972; 63629-2384; 43063-646; 71205-250; 70518-2278; 63629-7122; 43063-961; 68788-7740; 43547-404; 53489-676; 63629-2388; 55289-624; 63629-8201; 43063-654; 72189-253; 10702-067; 50436-0250; 72189-071; 43063-596; 55289-701; 71335-0419; 10702-029; 10702-001; 76420-108; 10702-026; 64980-190; 63629-1108; 50090-2536; 0792-0344; 10702-028; 63187-987; 61919-186; 63629-2477; 72189-203; 0527-1742; 11534-157; 50090-1498; 43063-182; 63629-1042; 63629-1106; 68788-7823; 10702-025; 42806-810; 11534-176; 68788-8942; 63187-800; 70934-474; 50090-0416; 0185-0644; 50436-0101; 65319-1452; 72789-208; 50090-0415; 43063-437; 71335-1591; 50090-3992; 63629-1043; 68788-8950; 68071-3241; 63629-1045; 71335-0678; 53002-7931; 71335-0161; 71335-0030; 63629-5075; 51927-2937; 63187-515; 63629-2383; 10702-027; 50090-1499; 63187-512; 13107-105; 71335-0350; 71335-1933; 68382-704; 13107-061; 50090-5493; 50090-3535; 71335-1860; 71205-564; 71335-0646; 0792-0345; 64850-810; 50090-4216; 68788-7906; 76420-057; 63629-2949; 63629-2385; 0527-1743; 50090-0653; 0527-0597; 63629-2386; 51224-203; 38779-0854; 50090-1679; 17337-0030; 66267-166; 63629-8528; 51224-101; 68071-4919; 50436-0202; 63629-4385; 63629-3211; 70771-1201; 13107-106; 63629-1040; 68382-703; 50090-3282; 63629-7874; 42806-524; 63629-8152; 63629-8537; 71205-340; 68382-670; 63629-1044; 70771-1202; 0527-1438; 45865-556; 70771-1200 |
Synonyms |
Phentermine | Duromine | Phentermine Hydrochloride | Hydrochloride, Phentermine | Adipex-P | Adipex P | AdipexP | Ionamine |