Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Phendimetrazine tartrate
Drug ID BADD_D01749
Description Phendimetrazine is a weight loss medication. Phendimetrazine is chemically related to amphetamines and is a Schedule III drug under the Convention on Psychotropic Substances and in the US since 1970.
Indications and Usage Used in the management of exogenous obesity as a short term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction.
Marketing Status Prescription; Discontinued
ATC Code Not Available
DrugBank ID DB01579
KEGG ID D02080
MeSH ID C100294
PubChem ID 120608
TTD Drug ID D0T6SU
NDC Product Code 50090-2592; 50090-2235; 0185-4057; 63629-3051; 68071-3040; 17337-0029; 69543-410; 63629-7266; 10702-045; 50090-0715; 43063-510; 10702-077; 50090-3976; 50090-3988; 71335-1840; 71335-0324; 69543-413; 63629-8536; 68788-7236; 51927-5043; 43063-892; 68071-2605; 69543-409; 63187-898; 68071-3062; 10702-078; 71335-0074; 66267-394; 64850-440; 0185-5254; 50090-5859; 63629-2489
Synonyms phendimetrazine | X-Trozine | Di-Ap-Trol | Dyrexan | Hyrex | Melfiat | Obezine | phendimetrazine hydrochloride | phendimetrazine hydrochloride, (2S-trans)-isomer | phendimetrazine tartrate | phendimetrazine tartrate, (2S-trans(R-(R*,R*)))-isomer | phendimetrazine tartrate, (R-(R*,R*))-isomer | phendimetrazine, (2R-cis)-isomer | phendimetrazine, (2S-trans)-isomer | phendimetrazine, trans(+-)-isomer | Prelu-2 | Trimstat | Wehless | Weightrol | Adipost | Bontril
Chemical Information
Molecular Formula C16H23NO7
CAS Registry Number 50-58-8
SMILES CC1C(OCCN1C)C2=CC=CC=C2.C(C(C(=O)O)O)(C(=O)O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain upper07.01.05.003--
Agitation19.06.02.001; 17.02.05.012--
Blood pressure increased13.14.03.005--Not Available
Constipation07.02.02.001--
Diarrhoea07.02.01.001--
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Dry mouth07.06.01.002--
Dysuria20.02.02.002--
Flushing24.03.01.002; 23.06.05.003; 08.01.03.025--
Headache17.14.01.001--
Hyperhidrosis23.02.03.004; 08.01.03.028--
Insomnia19.02.01.002; 17.15.03.002--
Nausea07.01.07.001--
Palpitations02.01.02.003--
Pollakiuria20.02.02.007--
Restlessness19.11.02.002; 17.02.05.021--
Tachycardia02.03.02.007--Not Available
Tremor17.01.06.002--
Vision blurred06.02.06.007; 17.17.01.010--
Ischaemic cardiomyopathy24.04.04.019; 02.04.01.004--Not Available
Libido disorder21.03.02.006; 19.08.03.004--Not Available
Cardiac valve disease02.07.02.001--Not Available
Psychotic disorder19.03.01.002--
Device stimulation issue27.01.02.005--Not Available
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