Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Pentosan polysulfate
Drug ID BADD_D01728
Description Pentosan polysulfate is a sulfated pentosyl polysaccharide with heparin-like properties.
Indications and Usage For the relief of bladder pain or discomfort associated with interstitial cystitis.
Marketing Status approved
ATC Code G04BX15; C05BA04
DrugBank ID DB00686
KEGG ID D05428
MeSH ID D010426
PubChem ID 37720
TTD Drug ID D0F8CM
NDC Product Code Not Available
UNII F59P8B75R4
Synonyms Pentosan Sulfuric Polyester | Polyester, Pentosan Sulfuric | Sulfuric Polyester, Pentosan | Pentosane Sulfuric Polyester | Polyester, Pentosane Sulfuric | Sulfuric Polyester, Pentosane | Xylan Sulfate | Sulfate, Xylan | Polypentose Sulfate | Sulfate, Polypentose | Polysulfated Xylan | Xylan, Polysulfated | Fibrocid | Hemoclar | HOE-BAY-946 | HOE BAY 946 | HOE-BAY 946 | BAY-946 | BAY 946 | HOE-946 | HOE 946 | Xylan SP54 | SP54, Xylan | Pentosan Polysulphate Sodium | Polysulphate Sodium, Pentosan | Sodium, Pentosan Polysulphate | Pentosan Polysulfate Sodium | Polysulfate Sodium, Pentosan | Sodium, Pentosan Polysulfate | PZ-68 | PZ 68 | PZ68 | SP-54 | SP 54 | SP54 | Tavan SP 54 | SP 54, Tavan | Elmiron | Pentosan Polysulfate | Polysulfate, Pentosan
Chemical Information
Molecular Formula C10H18O21S4
CAS Registry Number 37300-21-3
SMILES C1C(C(C(C(O1)OC2COC(C(C2OS(=O)(=O)O)OS(=O)(=O)O)O)OS(=O)(=O)O)OS(=O)(=O)O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Rhinitis11.01.13.004; 22.07.03.006--
Sinusitis22.07.03.007; 11.01.13.005--
Stomatitis07.05.06.005--
Subarachnoid haemorrhage24.07.04.004; 17.08.01.010; 12.01.10.011--Not Available
Thrombocytopenia01.08.01.002--Not Available
Tinnitus17.04.07.004; 04.04.01.002--
Urethritis20.07.02.001; 11.01.14.008--
Urticaria23.04.02.001; 10.01.06.001--
Vaginal infection11.01.10.002; 21.14.02.002--
Vomiting07.01.07.003--
Weight decreased13.15.01.005--
Weight increased13.15.01.006--
Musculoskeletal discomfort15.03.04.001--Not Available
Affect lability19.04.01.001--Not Available
Prostate cancer21.04.02.002; 16.25.01.001--Not Available
Decreased appetite08.01.09.028; 14.03.01.005--
Ill-defined disorder08.01.03.049--Not Available
Urethritis noninfective20.07.02.002--Not Available
Liver function test increased13.03.04.031--Not Available
Heavy menstrual bleeding21.01.03.005--Not Available
Vulvovaginal inflammation21.14.02.014--Not Available
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