Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Paricalcitol
Drug ID BADD_D01676
Description Paricalcitol is a synthetic vitamin D analog. Paricalcitol has been used to reduce parathyroid hormone levels. Paricalcitol is indicated for the prevention and treatment of secondary hyperparathyroidism associated with chronic renal failure.
Indications and Usage For treatment of secondary hyperparathyroidism associated with chronic kidney disease (CKD) Stage 3 and 4
Marketing Status approved; investigational
ATC Code H05BX02
DrugBank ID DB00910
KEGG ID D00930
MeSH ID C084656
PubChem ID 5281104
TTD Drug ID D0N1TP
NDC Product Code 0074-1658; 0074-4637; 0074-9036; 0143-9624; 65162-823; 65862-936; 70121-1035; 43598-565; 55150-213; 67457-379; 66499-0019; 16729-311; 43598-562; 55150-215; 68382-331; 65862-938; 67457-692; 69452-147; 10888-8103; 10888-8104; 11014-0334; 48943-0033; 58032-1001; 68513-1054; 49483-689; 55150-212; 68382-330; 69452-145; 70121-1033; 70121-1034; 10888-8102; 14474-021; 0143-9625; 49483-687; 65862-937; 11014-0048; 55111-663; 70121-1036; 58272-192; 0074-9037; 43598-563; 49483-688; 55111-665; 63629-2452; 67457-380; 16729-310; 25000-017; 0143-9596; 55150-214; 63629-2453; 65162-822; 67457-389; 69452-146; 25000-014; 43598-564; 55111-664; 65162-824; 11014-0053; 25000-012
UNII 6702D36OG5
Synonyms paricalcitol | 19-nor-1alpha,25-dihydroxyvitamin D2 | 19-nor-1,25-(OH)2D2 | Zemplar | paricalcitol-d6
Chemical Information
Molecular Formula C27H44O3
CAS Registry Number 131918-61-1
SMILES CC(C=CC(C)C(C)(C)O)C1CCC2C1(CCCC2=CC=C3CC(CC(C3)O)O)C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Breast cancer21.05.01.003; 16.10.01.001--Not Available
Breast pain21.05.05.003--
Breast tenderness21.05.05.004--Not Available
Bronchitis22.07.01.001; 11.01.09.001--
Calcinosis08.03.04.002--Not Available
Cardiac arrest02.03.04.0010.073578%
Cardiac failure02.05.01.0010.181492%
Cardio-respiratory arrest02.03.04.002; 22.02.06.0070.144213%Not Available
Cardiovascular disorder02.11.01.010; 24.03.02.0090.138327%Not Available
Cerebral ischaemia24.04.06.003; 17.08.01.0050.003924%
Cerebrovascular accident17.08.01.007; 24.03.05.0010.134403%
Cerebrovascular disorder24.03.05.002; 17.08.02.0020.046109%Not Available
Cervix carcinoma21.06.02.001; 16.12.01.0010.001962%Not Available
Chest discomfort22.12.02.002; 08.01.08.019; 02.02.02.009--Not Available
Chest pain22.12.02.003; 08.01.08.002; 02.02.02.011--Not Available
Chills15.05.03.016; 08.01.09.001--
Choking sensation22.12.03.004; 19.01.02.0020.001962%Not Available
Colitis07.08.01.001--
Colon cancer16.13.01.001; 07.21.01.0010.005886%Not Available
Condition aggravated08.01.03.004--Not Available
Confusional state19.13.01.001; 17.02.03.005--
Conjunctivitis11.01.06.012; 06.04.01.002--
Constipation07.02.02.001--
Cough22.02.03.001--
Death08.04.01.0013.039263%
Decubitus ulcer23.03.11.0060.001962%Not Available
Dehydration14.05.05.001--
Delirium19.13.02.001--
Depressed level of consciousness17.02.04.002--
Depression19.15.01.001--
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ADReCS-Target
Drug Name ADR Term Target
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