Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Oxycodone hydrochloride
Drug ID BADD_D01646
Description Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917.[A178696] It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period.[Label] The first oxycodone containing product, Percodan, was approved by the FDA on April 12, 1950.[L6460]
Indications and Usage For the treatment of diarrhoea, pulmonary oedema and for the relief of moderate to moderately severe pain.
Marketing Status Prescription; Discontinued
ATC Code N02AA05
DrugBank ID DB00497
KEGG ID D00847
MeSH ID D010098
PubChem ID 5462350
TTD Drug ID D07WPQ
NDC Product Code 17856-0826; 68084-975; 68094-005; 42806-005; 70752-136; 68084-983; 0406-0552; 31722-110; 68382-795; 10702-008; 64950-354; 10702-018; 68084-968; 42858-004; 49452-0034; 42806-007; 48433-347; 59011-415; 63629-1174; 42858-010; 61919-820; 0121-4839; 63629-1929; 42806-009; 63629-7399; 66689-401; 59011-440; 10702-056; 69988-0034; 64950-353; 42858-001; 67296-1040; 38779-0725; 72865-128; 59011-460; 0093-5733; 57664-370; 71335-1413; 71335-1422; 42858-005; 43386-431; 61960-9143; 43386-434; 67296-1376; 62559-167; 0904-6828; 67296-1595; 63629-8526; 60687-406; 63629-2104; 0406-8530; 0093-5734; 10702-171; 50383-964; 59011-430; 72189-094; 13107-055; 64950-901; 68084-354; 51634-0002; 59011-420; 68382-793; 67296-1324; 63629-4606; 31722-109; 10702-057; 60429-517; 55700-509; 68382-794; 10702-023; 23635-580; 68382-797; 67296-1560; 0406-8520; 0115-1559; 42858-002; 0115-1557; 63629-1928; 69344-213; 0093-5731; 67509-006; 17856-0920; 60429-519; 13107-056; 72189-095; 68308-145; 0904-6743; 68308-020; 0904-6445; 70752-137; 71335-1009; 71930-022; 55700-174; 63629-8889; 63629-1927; 71335-1421; 72865-129; 71930-023; 63629-8890; 0406-8556; 57664-224; 0115-1562; 68071-2536; 57664-187; 31722-111; 43386-430; 31722-917; 57664-371; 13107-057; 42806-008; 0904-6678; 17856-0390; 71335-0115; 42858-003; 61919-048; 47781-263; 50383-961; 68094-801; 31722-918; 60432-706; 71335-1414; 61919-444; 0115-1560; 42806-006; 59011-410; 71335-1361; 0054-0390; 10702-183; 0406-8515; 0121-0827; 0591-2708; 68462-347; 0093-5732; 47781-265; 68382-796; 60429-520; 66689-403; 0121-4827; 23635-582; 51927-1008; 68462-204; 47781-264; 59011-480; 67296-0832; 0406-8510; 63629-3775; 69344-113; 0792-2936; 0121-0826; 43386-433; 60429-521; 0115-1556; 57664-223; 71335-1245; 62559-151; 0904-6444; 60429-516; 0406-8557; 67296-0425; 0115-1561; 63629-1930; 43386-920; 43386-432; 66689-025; 10702-009; 0115-1558; 68071-2368; 0527-1774; 0591-2693; 23635-581
Synonyms Oxycodone | Dihydrone | Oxycone | Dihydrohydroxycodeinone | Oxycodeinon | Eucodal | Theocodin | Oxycodone Hydrochloride | Oxycontin | Pancodine | Dinarkon | Oxiconum
Chemical Information
Molecular Formula C18H22ClNO4
CAS Registry Number 124-90-3
SMILES CN1CCC23C4C(=O)CCC2(C1CC5=C3C(=C(C=C5)OC)O4)O.Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Abnormal dreams19.02.03.001; 17.15.02.001--Not Available
Agitation19.06.02.001; 17.02.05.012--
Amblyopia06.02.01.001--Not Available
Amenorrhoea21.01.02.001; 05.05.01.002--
Amnesia17.03.02.001; 19.20.01.001--
Anaemia01.03.02.001--
Anaphylactic reaction24.06.03.006; 10.01.07.001--
Anaphylactoid reaction24.06.03.007; 10.01.07.003--Not Available
Anxiety19.06.02.002--
Apnoea22.02.01.001--
Arthralgia15.01.02.001--
Arthritis15.01.01.001--
Asthenia08.01.01.001--Not Available
Back pain15.03.04.005--
Bone pain15.02.01.001--
Bronchitis22.07.01.001; 11.01.09.001--
Cardiac arrest02.03.04.001--
Cardiac failure02.05.01.001--
Chest pain22.02.08.003; 08.01.08.002; 02.02.02.011--Not Available
Chills08.01.09.001; 15.05.03.016--
Choking22.02.05.001--Not Available
Cholestasis09.01.01.001--Not Available
Confusional state17.02.03.005; 19.13.01.001--
Constipation07.02.02.001--
Cough22.02.03.001--
Death08.04.01.001--
Dehydration14.05.05.001--
Dental caries07.09.01.001--
Dependence19.07.02.003--Not Available
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