Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Oxycodone
Drug ID BADD_D01645
Description Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917.[A178696] It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period.[Label] The first oxycodone containing product, Percodan, was approved by the FDA on April 12, 1950.[L6460]
Indications and Usage For the treatment of diarrhoea, pulmonary oedema and for the relief of moderate to moderately severe pain.
Marketing Status Prescription; Discontinued
ATC Code N02AA05
DrugBank ID DB00497
KEGG ID D05312
MeSH ID D010098
PubChem ID 5284603
TTD Drug ID D07WPQ
NDC Product Code 68071-5055; 0904-7180; 65162-047; 24510-115; 24510-130; 67651-0304; 65162-050; 71335-1023; 67651-0306; 67651-0305; 71335-0981; 24510-140; 71335-1080; 65162-051; 24510-120; 65162-048; 67877-625; 71335-0677; 65162-049; 67651-0303; 24510-110; 67877-623; 0904-6966; 67651-0302
Synonyms Oxycodone | Dihydrone | Oxycone | Dihydrohydroxycodeinone | Oxycodeinon | Eucodal | Theocodin | Oxycodone Hydrochloride | Oxycontin | Pancodine | Dinarkon | Oxiconum
Chemical Information
Molecular Formula C18H21NO4
CAS Registry Number 76-42-6
SMILES CN1CCC23C4C(=O)CCC2(C1CC5=C3C(=C(C=C5)OC)O4)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Gingivitis11.01.04.013; 07.09.03.0030.000093%
Glossitis07.14.01.001--Not Available
Glycosylated haemoglobin increased13.02.02.0050.000093%Not Available
Gout15.01.06.001; 14.09.01.001--Not Available
Haematemesis24.07.02.011; 07.12.02.0020.000186%Not Available
Haematochezia24.07.02.012; 07.12.02.003--Not Available
Haematuria24.07.01.047; 20.02.01.006--
Blood urine present13.13.02.002--Not Available
Haemoglobin13.01.05.018--Not Available
Haemoglobin increased13.01.05.0040.000093%
Haemolysis01.06.04.0020.000186%
Haemoptysis24.07.01.006; 02.01.02.006; 22.02.03.004--Not Available
Hallucination19.10.02.0020.001346%
Hallucination, visual19.10.02.004--Not Available
Head injury12.01.09.003--Not Available
Headache17.14.01.001--
Heart rate decreased13.14.04.0010.000139%Not Available
Heart rate increased13.14.04.0020.000557%Not Available
Hepatic cirrhosis09.01.04.0010.000061%Not Available
Hepatic encephalopathy17.13.01.003; 09.01.03.0060.000093%Not Available
Hepatic failure09.01.03.002--
Hepatic function abnormal09.01.02.0010.000557%Not Available
Hepatitis09.01.07.004--Not Available
Hepatitis C11.05.06.004; 09.01.09.0050.000139%Not Available
Hepatitis cholestatic09.01.01.0020.000139%Not Available
Hepatocellular injury09.01.07.0080.000186%Not Available
Hepatomegaly09.01.05.001--Not Available
Hernia08.01.04.0010.000279%Not Available
Herpes simplex23.09.03.001; 11.05.02.001--Not Available
Herpes zoster23.09.03.002; 11.05.02.0030.000325%
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