Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Oxycodone
Drug ID BADD_D01645
Description Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917.[A178696] It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period.[Label] The first oxycodone containing product, Percodan, was approved by the FDA on April 12, 1950.[L6460]
Indications and Usage For the treatment of diarrhoea, pulmonary oedema and for the relief of moderate to moderately severe pain.
Marketing Status Prescription; Discontinued
ATC Code N02AA05
DrugBank ID DB00497
KEGG ID D05312
MeSH ID D010098
PubChem ID 5284603
TTD Drug ID D07WPQ
NDC Product Code 68071-5055; 0904-7180; 65162-047; 24510-115; 24510-130; 67651-0304; 65162-050; 71335-1023; 67651-0306; 67651-0305; 71335-0981; 24510-140; 71335-1080; 65162-051; 24510-120; 65162-048; 67877-625; 71335-0677; 65162-049; 67651-0303; 24510-110; 67877-623; 0904-6966; 67651-0302
Synonyms Oxycodone | Dihydrone | Oxycone | Dihydrohydroxycodeinone | Oxycodeinon | Eucodal | Theocodin | Oxycodone Hydrochloride | Oxycontin | Pancodine | Dinarkon | Oxiconum
Chemical Information
Molecular Formula C18H21NO4
CAS Registry Number 76-42-6
SMILES CN1CCC23C4C(=O)CCC2(C1CC5=C3C(=C(C=C5)OC)O4)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Cyanosis24.03.01.007; 22.02.02.007; 02.01.02.0020.000232%
Cyst16.02.02.002; 08.03.05.0010.000093%Not Available
Cystitis20.03.02.002; 11.01.14.0010.000186%
Deafness04.02.01.001--Not Available
Deafness neurosensory04.02.01.002; 17.04.07.0010.000325%Not Available
Death08.04.01.0010.002083%
Decreased activity19.11.01.002; 08.01.01.0060.000186%Not Available
Decubitus ulcer23.03.11.0060.000093%Not Available
Dehydration14.05.05.0010.000975%
Delirium19.13.02.0010.005988%
Delirium tremens19.13.02.002; 12.03.01.037; 08.06.02.0060.000139%Not Available
Delusion19.10.01.0010.000093%
Dementia17.03.01.001; 19.20.02.0010.000139%Not Available
Dental caries07.09.01.0010.000418%
Dependence19.07.02.0030.000186%Not Available
Depressed level of consciousness17.02.04.0020.001300%
Depressed mood19.15.02.001--Not Available
Depression19.15.01.001--
Dermatitis23.03.04.0020.000139%Not Available
Dermatitis allergic23.03.04.003; 10.01.03.0140.000093%Not Available
Dermatitis bullous23.03.01.002--
Dermatitis exfoliative10.01.01.004; 23.03.07.001--
Diabetes mellitus14.06.01.001; 05.06.01.0010.000418%Not Available
Diarrhoea07.02.01.001--
Diplopia06.02.06.002; 17.17.01.005--Not Available
Discomfort08.01.08.003--Not Available
Disorientation17.02.05.015; 19.13.01.0020.000557%Not Available
Disseminated intravascular coagulation24.01.01.010; 01.01.02.0020.000036%
Disturbance in attention19.21.02.002; 17.03.03.0010.000371%
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
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