Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Oxycodone
Drug ID BADD_D01645
Description Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917.[A178696] It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period.[Label] The first oxycodone containing product, Percodan, was approved by the FDA on April 12, 1950.[L6460]
Indications and Usage For the treatment of diarrhoea, pulmonary oedema and for the relief of moderate to moderately severe pain.
Marketing Status Prescription; Discontinued
ATC Code N02AA05
DrugBank ID DB00497
KEGG ID D05312
MeSH ID D010098
PubChem ID 5284603
TTD Drug ID D07WPQ
NDC Product Code 68071-5055; 0904-7180; 65162-047; 24510-115; 24510-130; 67651-0304; 65162-050; 71335-1023; 67651-0306; 67651-0305; 71335-0981; 24510-140; 71335-1080; 65162-051; 24510-120; 65162-048; 67877-625; 71335-0677; 65162-049; 67651-0303; 24510-110; 67877-623; 0904-6966; 67651-0302
Synonyms Oxycodone | Dihydrone | Oxycone | Dihydrohydroxycodeinone | Oxycodeinon | Eucodal | Theocodin | Oxycodone Hydrochloride | Oxycontin | Pancodine | Dinarkon | Oxiconum
Chemical Information
Molecular Formula C18H21NO4
CAS Registry Number 76-42-6
SMILES CN1CCC23C4C(=O)CCC2(C1CC5=C3C(=C(C=C5)OC)O4)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Negative thoughts19.15.02.0120.000093%Not Available
Sopor17.02.04.021; 19.02.04.002--Not Available
General physical condition abnormal13.15.01.0400.000093%Not Available
Wound infection staphylococcal12.02.05.051; 11.02.05.0140.000093%Not Available
Coma neonatal18.04.04.008; 17.02.09.0080.000024%Not Available
Accidental death12.01.08.040; 08.04.01.0130.000024%Not Available
Stress cardiomyopathy24.04.04.026; 02.04.01.0120.000139%Not Available
Velopharyngeal incompetence22.04.05.020; 07.05.01.0200.000186%Not Available
Apparent death08.01.03.0620.000186%Not Available
Quality of life decreased13.18.01.0130.000371%Not Available
Gastrointestinal viral infection11.05.04.016; 07.19.02.0110.000093%Not Available
Acute lung injury22.01.03.0100.000073%Not Available
Hepatic cancer recurrent16.07.02.006; 09.04.02.0110.000024%Not Available
Eye contusion24.07.06.022; 12.01.04.024; 06.11.01.0110.000093%Not Available
Toxic leukoencephalopathy17.13.02.012; 12.03.01.0590.000133%Not Available
Disorganised speech19.19.02.005; 17.02.08.0170.000232%Not Available
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