Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Oxybutynin chloride
Drug ID BADD_D01644
Description Overactive bladder (OAB) is a common condition negatively impacting the lives of millions of patients worldwide. Due to its urinary symptoms that include nocturia, urgency, and frequency, this condition causes social embarrassment and a poor quality of life.[A185996,A185999] Oxybutynin, also marketed as Ditropan XL, is an anticholinergic medication used for the relief of overactive bladder symptoms that has been optimized for high levels of safety and efficacy since initial FDA approval in 1975.[A183782,L8648] This drug relieves undesirable urinary symptoms, increasing the quality of life for patients affected by OAB. It is often used as first-line therapy for OAB.[A185990]
Indications and Usage For the treatment of overactive bladder.
Marketing Status Prescription; OTC; Discontinued
ATC Code G04BD04
DrugBank ID DB01062
KEGG ID D00722
MeSH ID C005419
PubChem ID 91505
TTD Drug ID D0R1DH
NDC Product Code 50268-627; 62175-271; 50268-628; 70934-909; 23155-810; 71930-051; 43353-282; 65162-373; 43353-285; 67544-569; 64380-162; 71335-0669; 50090-4192; 62175-272; 50090-4307; 70518-3032; 0603-4975; 50090-2049; 71335-1014; 63629-2245; 43353-367; 54838-510; 65015-705; 50090-0318; 68084-610; 52817-260; 68788-8141; 49452-4953; 14539-653; 42291-633; 43063-790; 0904-6570; 27241-155; 68084-400; 50268-629; 63187-749; 64980-209; 51927-2455; 72789-049; 27241-157; 50090-4728; 70518-2688; 66064-1005; 63739-548; 65085-0013; 43063-931; 71335-1160; 63629-2244; 66267-642; 0832-0038; 0904-2821; 65162-372; 67296-1175; 64980-431; 62175-270; 68788-7785; 70954-005; 71610-394; 16729-317; 69452-121; 69452-119; 42291-634; 43353-978; 43353-284; 71335-0519; 27241-156; 51407-099; 54469-0007; 50458-810; 43063-851; 72888-030; 71610-277; 50090-5822; 50111-456; 43353-322; 63629-1354; 72189-130; 63629-8996; 69315-182; 71335-1494; 53808-1122; 70518-2388; 72189-131; 71335-0610; 72888-032; 55154-0657; 64980-210; 0904-7027; 69452-120; 49169-1019; 71610-347; 0615-3512; 38779-0384; 17856-0092; 70518-2710; 59651-656; 0023-5861; 42291-635; 72888-031; 60432-092; 65162-371; 70518-2640; 16729-319; 68084-480; 10702-201; 16729-318; 72189-132; 50090-4658; 68071-1875; 50090-4622; 63629-2246; 50458-805; 70518-1941; 64980-211; 71335-1690; 70518-2904
Synonyms oxybutynin | 4-(diethylamino)-2-butynyl-alpha-cyclohexyl-alpha-hydroxybenzeneacetate | 4-(diethylamino)-2-butynyl-alpha-phenylcyclohexaneglycolate | Zatur | Contimin | Cystonorm | Ditropan | Dridase | Cystrin | Dresplan | Driptane | gelnique | Gen-Oxybutynin | Novo-Oxybutynin | Nu-Oxybutyn | Oxyb AbZ | Oxybutin Holsten | Oxybuton | Oxybutynin AL | Oxybutynin AZU | Oxybutynin Heumann | Oxybutynin Hexal | oxybutynin hydrochloride | oxybutynin chloride | Oxybutynin Stada | oxybutynin von ct | Oxybutynin-Puren | Oxybutynin-ratiopharm | Oxymedin | Oxytrol | PMS-Oxybutynin | Pollakisu | Renamel | Ryol | Spasmex Oxybutynin | Spasyt | Tavor | Oxybugamma | Apo-Oxybutynin
Chemical Information
Molecular Formula C22H32ClNO3
CAS Registry Number 1508-65-2
SMILES CCN(CC)CC#CCOC(=O)C(C1CCCCC1)(C2=CC=CC=C2)O.Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Amblyopia06.02.01.001--Not Available
Asthenia08.01.01.001--Not Available
Constipation07.02.02.001--
Cycloplegia17.17.02.003; 06.05.03.002--Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Dry mouth07.06.01.002--
Hallucination19.10.02.002--
Hypohidrosis23.02.03.005; 08.01.03.029--
Insomnia19.02.01.002; 17.15.03.002--
Lacrimation decreased06.08.02.007--Not Available
Mydriasis17.02.11.003; 06.05.03.004--Not Available
Nausea07.01.07.001--
Palpitations02.01.02.003--
Rash23.03.13.001--Not Available
Restlessness19.11.02.002; 17.02.05.021--
Suppressed lactation21.05.02.003; 18.06.02.001--Not Available
Tachycardia02.03.02.007--Not Available
Urinary hesitation20.02.02.009--Not Available
Urinary retention20.02.02.011--
Vasodilation procedure25.03.01.001--Not Available
Gastrointestinal motility disorder07.02.03.001--Not Available
Erectile dysfunction21.03.01.007; 19.08.04.001--
The 1th Page    1    Total 1 Pages