Pharmaceutical Information |
Drug Name |
Oxazepam |
Drug ID |
BADD_D01636 |
Description |
Oxazepam is an intermediate-acting, 3-hydroxybenzodiazepine used in the treatment of alcohol withdrawal and anxiety disorders. Oxazepam, like related 3-hydroxybenzodiazepine [lorazepam], is considered less susceptible to pharmacokinetic variability based on patient-specific factors (e.g. age, liver disease) - this feature is advantageous as compared to other benzodiazepines, and is likely owing in part to oxazepam's relatively simple metabolism.[A203516] It is an active metabolite of both [diazepam] and [temazepam][A39486] and undergoes very little biotransformation following absorption, making it unlikely to participate in pharmacokinetic interactions.[L13895] |
Indications and Usage |
For the treatment of anxiety disorders and alcohol withdrawal. |
Marketing Status |
Prescription; Discontinued |
ATC Code |
N05BA04 |
DrugBank ID |
DB00842
|
KEGG ID |
D00464
|
MeSH ID |
D010076
|
PubChem ID |
4616
|
TTD Drug ID |
D09LDR
|
NDC Product Code |
62584-812; 43353-965; 62584-813; 0228-2067; 72166-009; 64330-015; 0228-2069; 67544-117; 71610-639; 0228-2073; 43353-980; 48087-0087; 62584-814; 12828-0024; 52817-292; 52817-290; 52817-291; 67544-268 |
Synonyms |
Oxazepam | Serax | Tazepam | Adumbran |
|
Chemical Information |
Molecular Formula |
C15H11ClN2O2 |
CAS Registry Number |
604-75-1 |
SMILES |
C1=CC=C(C=C1)C2=NC(C(=O)NC3=C2C=C(C=C3)Cl)O |
Chemical Structure |
|
|
ADR Related Proteins Induced by Drug |
ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
Not Available | Not Available | Not Available | Not Available | Not Available |
|
ADRs Induced by Drug |
|