Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Opium tincture
Drug ID BADD_D01619
Description Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805.[A176035] It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse.[A176050] Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength such as [codeine], [fentanyl], [methadone], [hydrocodone], [hydromorphone], [meperidine], and [oxycodone]. Morphine was granted FDA approval in 1941.[L12114]
Indications and Usage For the relief and treatment of severe pain.
Marketing Status Not Available
ATC Code A07DA02; N02AA02
DrugBank ID DB00295
KEGG ID D06499
MeSH ID D009020
PubChem ID Not Available
TTD Drug ID D0WE3O
NDC Product Code 59116-4580
Synonyms Morphine | Morphia | Morphine Chloride | Chloride, Morphine | Morphine Sulfate | Sulfate, Morphine | SDZ 202-250 | SDZ 202 250 | SDZ 202250 | SDZ202-250 | SDZ202 250 | SDZ202250 | Morphine Sulfate (2:1), Pentahydrate | MS Contin | Contin, MS | Oramorph SR | Duramorph | Morphine Sulfate (2:1), Anhydrous
Chemical Information
Molecular Formula Not Available
CAS Registry Number 57-27-2
SMILES Not Available
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Cardiac arrhythmiasMu-type opioid receptorP35372T47768Not Available
HyperpathiaProtein kinase C alpha typeP17252T12808Not Available
HyperpathiaMitogen-activated protein kinase 8P45983T40097Not Available
HyperpathiaTranscription factor JunP05412T69085Not Available
HyperpathiaMu-type opioid receptorP35372T47768Not Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Constipation07.02.02.001--
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Dysphoria19.04.02.004--Not Available
Euphoric mood19.04.02.006--
Nausea07.01.07.001--
Pruritus23.03.12.001--
Sedation17.02.04.005--Not Available
Vomiting07.01.07.003--
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