Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Norfloxacin
Drug ID BADD_D01587
Description A synthetic fluoroquinolone (fluoroquinolones) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA gyrase.
Indications and Usage For the treatment of urinary tract infection
Marketing Status approved
ATC Code J01MA06; S01AE02
DrugBank ID DB01059
KEGG ID D00210
MeSH ID D009643
PubChem ID 4539
TTD Drug ID D0Q2PE
NDC Product Code 53104-7517
UNII N0F8P22L1P
Synonyms Norfloxacin | MK-0366 | MK 0366 | MK-366 | MK 366 | MK0366 | MK366 | Noroxin | AM-0715 | AM 0715 | AM0715 | AM-715 | AM 715
Chemical Information
Molecular Formula C16H18FN3O3
CAS Registry Number 70458-96-7
SMILES CCN1C=C(C(=O)C2=CC(=C(C=C21)N3CCNCC3)F)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Urticaria23.04.02.001; 10.01.06.001--
Vasculitis24.12.04.027; 10.02.02.006--
Ventricular arrhythmia02.03.04.006--
Vertigo04.04.01.003; 17.02.12.002--
Vision blurred17.17.01.010; 06.02.06.007--
Visual impairment06.02.10.013--Not Available
Vomiting07.01.07.003--
Vulvovaginal candidiasis21.14.02.003; 11.03.03.005--Not Available
White blood cell count decreased13.01.06.012--
Tubulointerstitial nephritis20.05.02.002--Not Available
Hypoacusis04.02.01.006--
Peripheral swelling08.01.03.053; 02.05.04.015--Not Available
Acute coronary syndrome24.04.04.011; 02.02.02.015--Not Available
Protein urine present13.13.02.006--Not Available
Musculoskeletal discomfort15.03.04.001--Not Available
Anxiety disorder19.06.01.002--Not Available
Blood alkaline phosphatase increased13.04.02.004--
Mental disorder19.07.01.002--Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
Psychotic disorder19.03.01.002--
Vulvovaginal mycotic infection11.03.05.004; 21.14.02.004--Not Available
Anal pruritus07.03.03.002--Not Available
Anorectal discomfort07.03.03.003--Not Available
Vulvovaginal swelling21.08.02.016--Not Available
Liver function test increased13.03.04.031--Not Available
Urinary tract candidiasis20.08.02.018; 11.03.03.025--Not Available
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