| Drug Name |
Nisoldipine |
| Drug ID |
BADD_D01570 |
| Description |
Nisoldipine is a 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, nisoldipine prevents calcium-dependent smooth muscle contraction and subsequent vasoconstriction. Nisoldipine may be used in alone or in combination with other agents in the management of hypertension. |
| Indications and Usage |
For the treatment of hypertension. It may be used alone or in combination with other antihypertensive agents. |
| Marketing Status |
approved |
| ATC Code |
C08CA07 |
| DrugBank ID |
DB00401
|
| KEGG ID |
D00618
|
| MeSH ID |
D015737
|
| PubChem ID |
4499
|
| TTD Drug ID |
D0S5CU
|
| NDC Product Code |
0378-2097; 66993-473; 13672-042; 0378-2222; 0378-2099; 70515-503; 49706-1607; 13672-041; 13672-043; 0378-2223; 66993-472; 0378-2096; 0378-2098; 70515-501; 0378-2224; 66993-475; 70515-500 |
| UNII |
4I8HAB65SZ
|
| Synonyms |
Nisoldipine | Bay K 5552 |
