Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Nalbuphine
Drug ID BADD_D01519
Description A narcotic used as a pain medication. It appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid receptors. Nalbuphine is the only opioid analgesic that is not a controlled substance in the United States.
Indications and Usage For the relief of moderate to severe pain.
Marketing Status Prescription; Discontinued
ATC Code N02AF02
DrugBank ID DB00844
KEGG ID D08246
MeSH ID D009266
PubChem ID 5311304
TTD Drug ID D01KQA
NDC Product Code Not Available
Synonyms Nalbuphine | Nalbuphine Hydrochloride | Nalbuphine Serb | EN-2234A | EN 2234A | EN2234A | Nubain
Chemical Information
Molecular Formula C21H27NO4
CAS Registry Number 20594-83-6
SMILES C1CC(C1)CN2CCC34C5C(CCC3(C2CC6=C4C(=C(C=C6)O)O5)O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Vertigo04.04.01.003; 17.02.12.002--
Vision blurred17.17.01.010; 06.02.06.007--
Vomiting07.01.07.003--
Wheezing22.03.01.009--
Foetal death18.01.02.003; 08.04.01.011--
Depersonalisation/derealisation disorder19.14.01.004--Not Available
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