Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Mycophenolic acid
Drug ID BADD_D01508
Description Mycophenolic acid is an an immunosuppresant drug and potent anti-proliferative, and can be used in place of the older anti-proliferative azathioprine. It is usually used as part of triple therapy including a calcineurin inhibitor (ciclosporin or tacrolimus) and prednisolone. It is also useful in research for the selection of animal cells that express the E. coli gene coding for XGPRT (xanthine guanine phosphoribosyltransferase).
Indications and Usage For the prophylaxis of organ rejection in patients receiving allogeneic renal transplants, administered in combination with cyclosporine and corticosteroids.
Marketing Status Prescription; Discontinued
ATC Code L04AA06
DrugBank ID DB01024
KEGG ID D05096
MeSH ID D009173
PubChem ID 446541
TTD Drug ID D04FBR
NDC Product Code 70518-3218; 60429-016; 72322-1049; 68084-918; 0904-6785; 60505-2965; 68254-5001; 68254-5002; 0078-0385; 70748-218; 70518-3255; 68084-907; 0904-6786; 24979-160; 50268-559; 51187-0004; 0378-4201; 60505-2966; 67877-426; 52076-6215; 0378-4202; 16729-261; 67877-427; 16729-189; 72322-1048; 70436-172; 60429-017; 24979-161; 20076-0405; 0078-0386; 70436-173; 57885-0009; 65727-011; 70748-217
Synonyms Mycophenolic Acid | Mycophenolate Mofetil | Mofetil, Mycophenolate | Mycophenolic Acid Morpholinoethyl Ester | Cellcept | Mycophenolate Sodium | Sodium Mycophenolate | Mycophenolate, Sodium | Myfortic | Mycophenolate Mofetil Hydrochloride | Mofetil Hydrochloride, Mycophenolate | RS 61443 | RS-61443 | RS61443
Chemical Information
Molecular Formula C17H20O6
CAS Registry Number 24280-93-1
SMILES CC1=C2COC(=O)C2=C(C(=C1OC)CC=C(C)CCC(=O)O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Cytomegalovirus infection11.05.01.0020.003474%
Deafness04.02.01.001--Not Available
Death08.04.01.0010.006193%
Dehydration14.05.05.0010.006369%
Delirium19.13.02.001--
Delusional perception19.10.02.006--Not Available
Depressed level of consciousness17.02.04.002--
Depression19.15.01.001--
Dermatitis23.03.04.002--Not Available
Dermatitis bullous23.03.01.002--
Developmental delay08.01.03.037--Not Available
Diabetes mellitus14.06.01.001; 05.06.01.0010.008106%Not Available
Diarrhoea07.02.01.0010.023160%
Discomfort08.01.08.003--Not Available
Disorientation19.13.01.002; 17.02.05.0150.001737%Not Available
Disturbance in attention17.03.03.001; 19.21.02.0020.001158%
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.0040.007527%
Dizziness postural02.01.02.005; 24.06.02.008; 17.02.05.004--Not Available
Drug ineffective08.06.01.006--Not Available
Dry eye06.08.02.001--
Dry mouth07.06.01.0020.001158%
Dry throat22.02.05.004; 07.06.01.005--Not Available
Duodenal ulcer07.04.02.002--
Dysgeusia17.02.07.003; 07.14.03.001--
Dyspepsia07.01.02.001--
Dysphagia07.01.06.0030.005211%
Dysphonia22.02.05.005; 19.19.03.002; 17.02.08.0040.001158%
Dysphoria19.04.02.004--Not Available
Dyspnoea22.02.01.004; 02.01.03.0020.008685%
Dyspnoea exertional22.02.01.005; 02.01.03.0030.001158%Not Available
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