Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Mycophenolic acid
Drug ID BADD_D01508
Description Mycophenolic acid is an an immunosuppresant drug and potent anti-proliferative, and can be used in place of the older anti-proliferative azathioprine. It is usually used as part of triple therapy including a calcineurin inhibitor (ciclosporin or tacrolimus) and prednisolone. It is also useful in research for the selection of animal cells that express the E. coli gene coding for XGPRT (xanthine guanine phosphoribosyltransferase).
Indications and Usage For the prophylaxis of organ rejection in patients receiving allogeneic renal transplants, administered in combination with cyclosporine and corticosteroids.
Marketing Status Prescription; Discontinued
ATC Code L04AA06
DrugBank ID DB01024
KEGG ID D05096
MeSH ID D009173
PubChem ID 446541
TTD Drug ID D04FBR
NDC Product Code 70518-3218; 60429-016; 72322-1049; 68084-918; 0904-6785; 60505-2965; 68254-5001; 68254-5002; 0078-0385; 70748-218; 70518-3255; 68084-907; 0904-6786; 24979-160; 50268-559; 51187-0004; 0378-4201; 60505-2966; 67877-426; 52076-6215; 0378-4202; 16729-261; 67877-427; 16729-189; 72322-1048; 70436-172; 60429-017; 24979-161; 20076-0405; 0078-0386; 70436-173; 57885-0009; 65727-011; 70748-217
Synonyms Mycophenolic Acid | Mycophenolate Mofetil | Mofetil, Mycophenolate | Mycophenolic Acid Morpholinoethyl Ester | Cellcept | Mycophenolate Sodium | Sodium Mycophenolate | Mycophenolate, Sodium | Myfortic | Mycophenolate Mofetil Hydrochloride | Mofetil Hydrochloride, Mycophenolate | RS 61443 | RS-61443 | RS61443
Chemical Information
Molecular Formula C17H20O6
CAS Registry Number 24280-93-1
SMILES CC1=C2COC(=O)C2=C(C(=C1OC)CC=C(C)CCC(=O)O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Aplasia pure red cell10.02.01.003; 01.03.03.001--Not Available
Apnoea22.02.01.001--
Arrhythmia02.03.02.001--Not Available
Arterial thrombosis24.01.01.002--Not Available
Arthralgia15.01.02.001--
Arthritis15.01.01.0010.000604%
Arthropathy15.01.01.003--Not Available
Ascites09.01.05.003; 07.07.01.001; 02.05.04.0020.001158%
Aspartate aminotransferase increased13.03.01.0060.001158%
Asthenia08.01.01.0010.005211%Not Available
Asthma22.03.01.002; 10.01.03.010--Not Available
Ataxia17.02.02.001; 08.01.02.004--
Atelectasis22.01.02.001--
Atrial fibrillation02.03.03.0020.002895%
Atrial flutter02.03.03.003--
Atrophy08.03.04.001--Not Available
Back pain15.03.04.0050.002895%
Basal cell carcinoma23.08.02.001; 16.03.02.001--Not Available
Benign neoplasm of skin23.10.01.006; 16.26.01.006--Not Available
Bladder pain20.02.02.001--Not Available
Blindness17.17.01.003; 06.02.02.0010.001057%Not Available
Blood bilirubin increased13.03.01.0080.001158%
Blood creatinine increased13.13.01.0040.010422%
Blood glucose increased13.02.02.0020.002895%Not Available
Blood iron decreased13.11.01.0060.001158%Not Available
Blood lactate dehydrogenase increased13.04.02.002--
Blood pressure increased13.14.03.0050.001737%Not Available
Blood urea increased13.13.01.006--Not Available
Blood uric acid increased13.02.04.0010.001158%Not Available
Body temperature increased13.15.01.001--Not Available
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