Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Moxifloxacin hydrochloride
Drug ID BADD_D01502
Description Moxifloxacin is a synthetic fluoroquinolone antibiotic agent. Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.
Indications and Usage For the treatment of sinus and lung infections such as sinusitis, pneumonia, and secondary infections in chronic bronchitis. Also for the treatment of bacterial conjunctivitis (pinkeye).
Marketing Status Prescription; Discontinued
ATC Code J01MA14; S01AE07
DrugBank ID DB00218
KEGG ID D00874
MeSH ID D000077266
PubChem ID 101526
TTD Drug ID D0ZV0Z
NDC Product Code 60429-893; 58032-0131; 65862-603; 51991-943; 0065-0006; 50268-576; 49574-522; 72789-037; 48943-0025; 72789-038; 51927-0167; 0832-1410; 48943-0024; 68084-722; 13668-201; 57237-156; 66298-8507; 0781-7135; 29967-0005; 0065-4013; 63323-850; 0078-0939; 50370-0001; 0093-7387; 67457-323; 67296-1616; 50090-4100; 65862-627; 50090-4058; 55111-064; 49587-106; 40032-034; 51927-4833; 51927-0089
Synonyms Moxifloxacin | 1-Cyclopropyl--7-(2,8-diazabicyclo(4.3.0)non-8-yl)-6-fluoro-8-methoxy-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid | Octegra | Proflox | Moxifloxacin Hydrochloride | Avelox | Avalox | Izilox | Actira | BAY 12-8039 | BAY 12 8039 | BAY-12-8039 | BAY 128039 | BAY-128039 | BAY128039
Chemical Information
Molecular Formula C21H25ClFN3O4
CAS Registry Number 186826-86-8
SMILES COC1=C2C(=CC(=C1N3CC4CCCNC4C3)F)C(=O)C(=CN2C5CC5)C(=O)O.Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Arthralgia15.01.02.001--
Arthritis15.01.01.001--
Arthropathy15.01.01.003--Not Available
Aspartate aminotransferase increased13.03.01.006--
Asthenia08.01.01.001--Not Available
Asthma22.03.01.002; 10.01.03.010--Not Available
Atrial fibrillation02.03.03.002--
Atrial flutter02.03.03.003--
Atrioventricular block first degree02.03.01.004--
Back pain15.03.04.005--
Balanoposthitis21.09.03.001--Not Available
Basophil count decreased13.01.06.001--Not Available
Bladder pain20.02.02.001--Not Available
Blindness06.02.02.001; 17.17.01.003--Not Available
Blood albumin increased13.09.01.002--Not Available
Blood bilirubin increased13.03.01.008--
Blood chloride increased13.11.01.005--Not Available
Blood creatinine increased13.13.01.004--
Blood glucose decreased13.02.02.001--Not Available
Blood glucose increased13.02.02.002--Not Available
Blood lactate dehydrogenase increased13.04.02.002--
Blood pressure increased13.14.03.005--Not Available
Blood thromboplastin decreased13.01.02.005--Not Available
Blood triglycerides increased13.12.03.001--Not Available
Blood urea increased13.13.01.006--Not Available
Blood uric acid increased13.02.04.001--Not Available
Body temperature increased13.15.01.001--Not Available
Bone disorder15.02.04.004--Not Available
Bradycardia02.03.02.002--Not Available
Bronchospasm10.01.03.012; 22.03.01.004--
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