Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Moxifloxacin
Drug ID BADD_D01501
Description Moxifloxacin is a synthetic fluoroquinolone antibiotic agent. Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.
Indications and Usage For the treatment of sinus and lung infections such as sinusitis, pneumonia, and secondary infections in chronic bronchitis. Also for the treatment of bacterial conjunctivitis (pinkeye).
Marketing Status Prescription; Discontinued
ATC Code J01MA14; S01AE07
DrugBank ID DB00218
KEGG ID D08237
MeSH ID D000077266
PubChem ID 152946
TTD Drug ID D0ZV0Z
NDC Product Code 50090-3147; 0904-6406; 0378-5430; 65977-0038; 12527-0517; 17478-519; 72189-334; 72789-233; 50090-5279; 60505-0582; 67296-1679; 65862-840; 61919-553; 68180-422; 68180-421; 63629-8357; 72189-321; 72189-076; 55111-112
Synonyms Moxifloxacin | 1-Cyclopropyl--7-(2,8-diazabicyclo(4.3.0)non-8-yl)-6-fluoro-8-methoxy-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid | Octegra | Proflox | Moxifloxacin Hydrochloride | Avelox | Avalox | Izilox | Actira | BAY 12-8039 | BAY 12 8039 | BAY-12-8039 | BAY 128039 | BAY-128039 | BAY128039
Chemical Information
Molecular Formula C21H24FN3O4
CAS Registry Number 151096-09-2
SMILES COC1=C2C(=CC(=C1N3CC4CCCNC4C3)F)C(=O)C(=CN2C5CC5)C(=O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Oral candidiasis11.03.03.004; 07.05.07.001--Not Available
Pain08.01.08.004--
Pain in extremity15.03.04.010--
Palpitations02.01.02.003--
Pancytopenia01.03.03.003--Not Available
Paraesthesia17.02.06.0050.000578%
Phlebitis24.05.03.001; 12.02.01.002--
Photophobia17.17.02.006; 06.01.01.0040.001735%
Photosensitivity reaction23.03.09.003--
Pneumonia22.07.01.003; 11.01.09.003--Not Available
PO2 decreased13.02.01.005--Not Available
Polyneuropathy17.09.03.012--Not Available
Prothrombin time prolonged13.01.02.012--Not Available
Prothrombin time ratio decreased13.01.02.040--Not Available
Prothrombin time ratio increased13.01.02.041--Not Available
Pruritus23.03.12.0010.000868%
Pyrexia08.05.02.003--
Rash23.03.13.0010.001735%Not Available
Rash generalised23.03.13.0020.000578%Not Available
Red blood cell count decreased13.01.05.007--Not Available
Renal failure20.01.03.005--Not Available
Respiratory distress22.02.01.0120.000578%Not Available
Restlessness19.11.02.002; 17.02.05.021--
Somnolence19.02.05.003; 17.02.04.0060.000578%
Stevens-Johnson syndrome10.01.03.020; 23.03.01.007; 12.03.01.014; 11.07.01.005--
Suicidal ideation19.12.01.003--
Suicide attempt19.12.01.004--
Swollen tongue07.14.02.003; 23.04.01.014; 10.01.05.0150.000578%Not Available
Syncope24.06.02.012; 17.02.04.008; 02.01.02.008--
Tachycardia02.03.02.007--Not Available
The 6th Page    First    Pre   6 7 8    Next   Last    Total 8 Pages