Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Monobenzone
Drug ID BADD_D01493
Description Monobenzone is the monobenzyl ether of hydroquinone used medically for depigmentation. Monobenzone occurs as a white, almost tasteless crystalline powder, soluble in alcohol and practically insoluble in water. It exerts a depigmenting effect on skin of mammals by increasing the excretion of melanin from the melanocytes. It may also cause destruction of melanocytes and permanent depigmentation.
Indications and Usage Used topically to treat the loss of skin color (vitiligo).
Marketing Status Discontinued
ATC Code D11AX13
DrugBank ID DB00600
KEGG ID D05072
MeSH ID C006429
PubChem ID 7638
TTD Drug ID D0H6TP
NDC Product Code 71052-111; 73309-070
Synonyms monobenzone | hydroquinone monobenzyl ether | agerite alba | monobenzyl ether hydroquinone | p-(benzyloxy)phenol | Benoquin | Novo-depigman
Chemical Information
Molecular Formula C13H12O2
CAS Registry Number 103-16-2
SMILES C1=CC=C(C=C1)COC2=CC=C(C=C2)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Burning sensation17.02.06.001; 08.01.09.029--Not Available
Dermatitis23.03.04.002--Not Available
Eczema23.03.04.006--
Rash erythematous23.03.06.003--Not Available
Skin disorder23.03.03.007--Not Available
Skin irritation23.03.04.009--Not Available
Sensitisation08.01.05.009; 10.02.01.012--Not Available
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