Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Mometasone furoate
Drug ID BADD_D01491
Description Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and certain skin conditions[FDA Label][F4292,F4295]. It has a glucocorticoid receptor binding affinity 22 times stronger than [dexamethasone] and higher than many other corticosteroids as well[A176906]. Mometasone furoate is formulated as a dry powder inhaler, nasal spray, and ointment for its different indications[FDA Label][F4292,F4295].
Indications and Usage The inhaler is indicated for the maintenance treatment of asthma as prophylactic therapy. The nasal spray is indicated for the treatment of the nasal symptoms of seasonal allergic and perennial allergic rhinitis.
Marketing Status Prescription; Discontinued
ATC Code D07AC13; D07XC03; R01AD09; R03BA07
DrugBank ID DB14512
KEGG ID D00690
MeSH ID D000068656
PubChem ID 441336
TTD Drug ID D03HYX
NDC Product Code 63187-288; 78206-111; 63629-8681; 63190-0730; 10599-003; 63629-8686; 62991-3098; 16714-974; 68462-225; 0168-0270; 63629-8682; 60429-664; 63187-432; 11517-434; 71161-133; 64918-0330; 50090-1026; 71205-413; 51552-1510; 0713-0634; 0168-0272; 68462-385; 78206-115; 10695-111; 50909-5151; 78206-114; 0713-0635; 64918-0424; 13668-527; 78206-112; 70518-3244; 46439-8733; 63592-0387; 68462-192; 58175-1234; 52128-163; 0168-0271; 0713-0701; 63190-0340; 63592-0397; 45802-118; 60505-0830; 53002-8320; 70518-2883; 78206-113; 68071-4637; 63629-8683; 15308-0220; 51672-1311; 75895-0280; 63629-8685; 75895-0279; 11517-222; 0713-0726; 68071-4460; 68071-1538; 65089-0025; 11517-433; 22552-0002; 45802-119; 53104-7646; 51927-4506; 53002-8321; 45802-257; 0713-0727; 63629-8684; 38779-2413; 51672-1305; 51672-1315
Synonyms Mometasone Furoate | Furoate, Mometasone | Nasonex | Mometasone Furoate Monohydrate | Furoate Monohydrate, Mometasone | Monohydrate, Mometasone Furoate | Asmanex Twisthaler | Twisthaler, Asmanex | Asmanex | Rinelon | Elocon | Sch 32088 | Sch-32088 | Sch32088 | Mometasone
Chemical Information
Molecular Formula C27H30Cl2O6
CAS Registry Number 83919-23-7
SMILES CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CCl)OC(=O)C5=CC=CO5)C)O)Cl)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Nausea07.01.07.001--
Nervousness19.06.02.0030.000497%Not Available
Neuralgia17.02.07.0050.000497%
Neuropathy peripheral17.09.03.003--Not Available
Ocular hyperaemia06.04.05.0040.001243%Not Available
Oral candidiasis11.03.03.004; 07.05.07.0010.000746%Not Available
Osteonecrosis24.04.05.004; 15.02.04.0070.000746%
Otitis media11.01.05.004; 04.05.01.001--
Pain08.01.08.004--
Pain in extremity15.03.04.010--
Pain of skin23.03.03.0030.000497%
Palpitations02.01.02.0030.001492%
Paraesthesia17.02.06.005--
Parosmia22.04.03.007; 17.04.04.0020.000195%Not Available
Periorbital oedema23.04.01.002; 06.08.03.017; 10.01.05.0100.000746%
Pharyngitis22.07.03.004; 11.01.13.003; 07.05.07.004--
Pneumonia22.07.01.003; 11.01.09.003--Not Available
Pneumonitis22.01.01.0060.000497%
Productive cough22.02.03.0050.001492%
Pruritus23.03.12.001--
Psoriasis23.03.14.002; 10.02.01.036--Not Available
Psychomotor hyperactivity19.11.02.003; 17.01.02.0110.000746%Not Available
Pulmonary congestion24.03.08.001; 22.01.03.002; 02.05.02.0020.000497%Not Available
Pustular psoriasis23.03.14.006--Not Available
Pyrexia08.05.02.003--
Rash23.03.13.001--Not Available
Rash erythematous23.03.06.0030.000497%Not Available
Rash generalised23.03.13.0020.000994%Not Available
Respiration abnormal22.02.08.0110.000746%Not Available
Respiratory disorder22.02.07.0020.001492%Not Available
The 5th Page    First    Pre   5 6 7 8    Next   Last    Total 8 Pages