Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Minoxidil
Drug ID BADD_D01473
Description A potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.
Indications and Usage For the treatment of severe hypertension and in the topical treatment (regrowth) of androgenic alopecia in males and females and stabilisation of hair loss in patients with androgenic alopecia.
Marketing Status Prescription; OTC; Discontinued
ATC Code C02DC01; D11AX01
DrugBank ID DB00350
KEGG ID D00418
MeSH ID D008914
PubChem ID 4201
TTD Drug ID D0Y2CJ
NDC Product Code 51927-2885; 37808-833; 51672-2129; 63981-798; 50383-001; 63981-032; 42291-619; 41250-749; 82269-607; 38779-0574; 49035-202; 69282-002; 43353-342; 40700-0008; 64162-0209; 69968-0030; 25280-007; 71176-781; 59640-000; 21130-819; 41250-428; 42291-618; 11673-919; 0113-1129; 68391-294; 69113-129; 11673-317; 71730-294; 56062-202; 49884-256; 56062-798; 41250-294; 0363-2294; 63486-015; 0591-5643; 0363-2798; 76003-0748; 57483-542; 11822-0202; 51552-0536; 0591-5642; 66219-0004; 69282-001; 71730-798; 49035-294; 68196-032; 51326-160; 11822-0129; 0113-0294; 72764-001; 68196-469; 63629-2232; 79481-0070; 59779-294; 41250-798; 41163-798; 21130-750; 37808-798; 57483-535; 72288-202; 63629-2230; 0009-5056; 63940-032; 56062-294; 30142-798; 68016-382; 71205-490; 68084-204; 59779-202; 46204-0159; 82157-100; 71713-092; 68981-036; 0113-0798; 51552-1334; 0009-5230; 57483-530; 71713-093; 11822-0702; 70550-605; 30142-632; 72484-095; 63940-491; 49035-746; 79974-201; 17337-0027; 0113-7294; 62991-1105; 81653-002; 73277-002; 54236-020; 0113-7202; 80855-201; 37808-202; 11673-431; 82157-200; 11822-0606; 69113-128; 0113-7798; 79572-022; 67438-015; 0363-1129; 0363-0703; 73277-001; 63629-1085; 71290-813; 79903-072; 0113-7129; 65121-101; 0363-7202; 56062-322; 63940-202; 46144-342; 25280-006; 69423-586; 51672-2128; 68196-823; 63629-1086; 11673-798; 63934-007; 71730-202; 11673-189; 63940-385; 0363-0032; 49035-798; 63981-380; 67438-020; 69968-0031; 0113-1032; 63629-2231; 69842-599; 49452-4780; 70550-503; 21130-273; 11673-632; 69968-0089; 72882-094; 53489-386; 11673-707; 65121-102; 68084-205; 72288-294; 37808-404; 11822-1033; 49539-001; 71713-091; 0472-0066; 80813-0022; 65121-562; 69968-0090; 57483-540; 63940-582; 0113-7032; 41250-202; 55301-094; 72764-002; 69842-797; 11822-0798; 63486-016; 49884-257; 71730-129; 11673-382; 21130-163; 59779-798; 53489-387; 30142-719; 11509-0798; 51326-161; 69842-598; 81653-001; 69423-587; 63981-294; 49035-905; 71724-400; 72288-129; 30142-294; 68016-006
Synonyms Minoxidil | Rogaine | Regaine | U 10858 | Loniten
Chemical Information
Molecular Formula C9H15N5O
CAS Registry Number 38304-91-5
SMILES C1CCN(CC1)C2=NC(=N)N(C(=C2)N)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Oedema14.05.06.010; 08.01.07.0060.009645%Not Available
Oedema peripheral14.05.06.011; 08.01.07.007; 02.05.04.0070.008038%
Oliguria20.01.03.0040.003215%Not Available
Palpitations02.01.02.0030.012860%
Paraesthesia17.02.06.0050.004823%
Pericardial effusion02.06.01.0020.035365%
Pericarditis02.06.02.001--
Pleural effusion22.05.02.0020.012860%
Pruritus23.03.12.0010.014468%
Psoriasis23.03.14.002; 10.02.01.0360.004823%Not Available
Pyrexia08.05.02.003--
Rash23.03.13.001--Not Available
Seborrhoea23.02.07.0010.004823%Not Available
Sinus tachycardia02.03.03.0100.004823%
Skin disorder23.03.03.007--Not Available
Skin hyperpigmentation23.05.01.0030.003215%
Skin irritation23.03.04.0090.003215%Not Available
Skin striae23.01.05.0020.003215%Not Available
Stevens-Johnson syndrome23.03.01.007; 12.03.01.014; 11.07.01.005; 10.01.03.020--
Swelling08.01.03.0150.006430%Not Available
Syncope24.06.02.012; 17.02.04.008; 02.01.02.0080.004823%
Tachycardia02.03.02.0070.022505%Not Available
Thrombocytopenia01.08.01.002--Not Available
Tinnitus17.04.07.004; 04.04.01.0020.003215%
Toxic epidermal necrolysis23.03.01.008; 12.03.01.015; 11.07.01.006; 10.01.01.006--
Virilism21.10.04.001; 05.05.01.001--
Vision blurred17.17.01.010; 06.02.06.0070.003215%
Vomiting07.01.07.0030.020898%
Weight increased13.15.01.0060.006430%
Retinal toxicity12.03.01.036; 06.09.03.0130.006430%Not Available
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