Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Minoxidil
Drug ID BADD_D01473
Description A potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.
Indications and Usage For the treatment of severe hypertension and in the topical treatment (regrowth) of androgenic alopecia in males and females and stabilisation of hair loss in patients with androgenic alopecia.
Marketing Status Prescription; OTC; Discontinued
ATC Code C02DC01; D11AX01
DrugBank ID DB00350
KEGG ID D00418
MeSH ID D008914
PubChem ID 4201
TTD Drug ID D0Y2CJ
NDC Product Code 51927-2885; 37808-833; 51672-2129; 63981-798; 50383-001; 63981-032; 42291-619; 41250-749; 82269-607; 38779-0574; 49035-202; 69282-002; 43353-342; 40700-0008; 64162-0209; 69968-0030; 25280-007; 71176-781; 59640-000; 21130-819; 41250-428; 42291-618; 11673-919; 0113-1129; 68391-294; 69113-129; 11673-317; 71730-294; 56062-202; 49884-256; 56062-798; 41250-294; 0363-2294; 63486-015; 0591-5643; 0363-2798; 76003-0748; 57483-542; 11822-0202; 51552-0536; 0591-5642; 66219-0004; 69282-001; 71730-798; 49035-294; 68196-032; 51326-160; 11822-0129; 0113-0294; 72764-001; 68196-469; 63629-2232; 79481-0070; 59779-294; 41250-798; 41163-798; 21130-750; 37808-798; 57483-535; 72288-202; 63629-2230; 0009-5056; 63940-032; 56062-294; 30142-798; 68016-382; 71205-490; 68084-204; 59779-202; 46204-0159; 82157-100; 71713-092; 68981-036; 0113-0798; 51552-1334; 0009-5230; 57483-530; 71713-093; 11822-0702; 70550-605; 30142-632; 72484-095; 63940-491; 49035-746; 79974-201; 17337-0027; 0113-7294; 62991-1105; 81653-002; 73277-002; 54236-020; 0113-7202; 80855-201; 37808-202; 11673-431; 82157-200; 11822-0606; 69113-128; 0113-7798; 79572-022; 67438-015; 0363-1129; 0363-0703; 73277-001; 63629-1085; 71290-813; 79903-072; 0113-7129; 65121-101; 0363-7202; 56062-322; 63940-202; 46144-342; 25280-006; 69423-586; 51672-2128; 68196-823; 63629-1086; 11673-798; 63934-007; 71730-202; 11673-189; 63940-385; 0363-0032; 49035-798; 63981-380; 67438-020; 69968-0031; 0113-1032; 63629-2231; 69842-599; 49452-4780; 70550-503; 21130-273; 11673-632; 69968-0089; 72882-094; 53489-386; 11673-707; 65121-102; 68084-205; 72288-294; 37808-404; 11822-1033; 49539-001; 71713-091; 0472-0066; 80813-0022; 65121-562; 69968-0090; 57483-540; 63940-582; 0113-7032; 41250-202; 55301-094; 72764-002; 69842-797; 11822-0798; 63486-016; 49884-257; 71730-129; 11673-382; 21130-163; 59779-798; 53489-387; 30142-719; 11509-0798; 51326-161; 69842-598; 81653-001; 69423-587; 63981-294; 49035-905; 71724-400; 72288-129; 30142-294; 68016-006
Synonyms Minoxidil | Rogaine | Regaine | U 10858 | Loniten
Chemical Information
Molecular Formula C9H15N5O
CAS Registry Number 38304-91-5
SMILES C1CCN(CC1)C2=NC(=N)N(C(=C2)N)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Agitation19.06.02.001; 17.02.05.0120.003215%
Alopecia23.02.02.0010.027328%
Angina pectoris24.04.04.002; 02.02.02.0020.004823%
Angina unstable24.04.04.004; 02.02.02.0040.003215%Not Available
Angioedema23.04.01.001; 10.01.05.0090.003215%Not Available
Asthenia08.01.01.001--Not Available
Atrial fibrillation02.03.03.0020.003215%
Atrial flutter02.03.03.0030.003215%
Blister12.01.06.002; 23.03.01.0010.003215%Not Available
Blood creatinine increased13.13.01.004--
Blood pressure decreased13.14.03.0020.003215%Not Available
Breast tenderness21.05.05.004--Not Available
Burning sensation17.02.06.001; 08.01.09.0290.008038%Not Available
Cardiac tamponade02.06.01.0010.004823%
Cellulitis23.09.01.001; 11.02.01.0010.004823%Not Available
Cerebral infarction24.04.06.002; 17.08.01.0040.003215%Not Available
Chest discomfort22.02.08.001; 08.01.08.019; 02.02.02.0090.003215%Not Available
Chest pain22.02.08.003; 08.01.08.002; 02.02.02.0110.003215%Not Available
Corneal abrasion12.01.04.001; 06.11.03.0010.003215%Not Available
Depression19.15.01.001--
Dermatitis23.03.04.0020.006430%Not Available
Dermatitis allergic23.03.04.003; 10.01.03.0140.004823%Not Available
Dermatitis bullous23.03.01.002--
Dermatitis contact23.03.04.004; 12.03.01.040; 10.01.01.0030.009645%Not Available
Dizziness02.01.02.004; 24.06.02.007; 17.02.05.0030.014468%
Drug abuse19.07.02.0100.000839%Not Available
Drug hypersensitivity10.01.01.0010.012860%Not Available
Dyspnoea22.02.01.004; 02.01.03.0020.009645%
Electrocardiogram abnormal13.14.05.001--Not Available
Electrocardiogram ST segment13.14.05.035--Not Available
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