Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Midodrine hydrochloride
Drug ID BADD_D01462
Description An ethanolamine derivative that is an adrenergic alpha agonist. It is used as a vasoconstrictor agent in the treatment of hypotension.
Indications and Usage For the treatment of symptomatic orthostatic hypotension (OH).
Marketing Status Prescription; Discontinued
ATC Code C01CA17
DrugBank ID DB00211
KEGG ID D01307
MeSH ID D008879
PubChem ID 18340
TTD Drug ID D02XJY
NDC Product Code 70700-158; 70700-157; 42291-560; 72888-112; 50268-563; 0904-6817; 0245-0213; 0615-8293; 68382-738; 72888-113; 71335-1433; 62332-338; 51407-390; 60687-398; 70985-007; 0378-1902; 63190-0080; 64980-434; 0245-0212; 72888-114; 70700-159; 0615-8291; 14593-917; 63629-2348; 52817-323; 0615-8384; 63629-7983; 70985-005; 63629-2227; 0615-8382; 63629-2347; 70771-1595; 46708-339; 0615-8383; 59651-248; 55154-8086; 62332-339; 42291-562; 51407-388; 46708-338; 60687-387; 71205-905; 49884-849; 68382-739; 64980-435; 51407-389; 49884-874; 42291-561; 59651-247; 55154-5623; 59651-246; 63629-2346; 62332-340; 60505-1320; 50268-562; 70771-1596; 71205-904; 0378-1903; 52817-325; 66583-0509; 71205-906; 71335-1705; 51079-453; 68382-737; 0904-6818; 49884-814; 60687-409; 70054-004; 60505-1321; 59285-043; 57451-1204; 60505-1325; 70985-006; 50268-561; 70771-1597; 64980-433; 0245-0211; 50384-0800; 63190-0720; 55154-5696; 0378-1901; 50384-0810; 0904-6819; 46708-340; 63629-6928; 52817-324; 63190-0580
Synonyms Midodrine | Midodrin | Midodrine Hydrochloride | Midodrine Monohydrochloride | Monohydrochloride, Midodrine | ProAmatine | Amatine | ST-1085 | ST 1085 | ST1085 | Gutron | Midon
Chemical Information
Molecular Formula C12H19ClN2O4
CAS Registry Number 43218-56-0
SMILES COC1=CC(=C(C=C1)OC)C(CNC(=O)CN)O.Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Somnolence19.02.05.003; 17.02.04.006--
Thinking abnormal17.02.05.023; 19.10.03.001--Not Available
Urinary retention20.02.02.011--
Visual field defect17.17.01.001; 06.02.07.003--Not Available
Vasodilation procedure25.03.01.001--Not Available
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