Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Mepivacaine hydrochloride
Drug ID BADD_D01388
Description A local anesthetic that is chemically related to bupivacaine but pharmacologically related to lidocaine. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)
Indications and Usage For production of local or regional analgesia and anesthesia by local infiltration, peripheral nerve block techniques, and central neural techniques including epidural and caudal blocks.
Marketing Status Prescription; Discontinued
ATC Code N01BB03
DrugBank ID DB00961
KEGG ID D00738
MeSH ID D008619
PubChem ID 66070
TTD Drug ID D0WO8W
NDC Product Code 0404-6730; 63323-283; 63323-294; 63323-260; 67239-0201; 42756-1080; 50090-4517; 66312-441; 43128-005; 0409-1067; 52932-0731; 63323-296; 0409-2047; 0362-1098; 66975-406; 0409-1041; 0409-1036; 66467-9760; 17381-261; 0409-1038; 0362-0753; 63323-293; 50227-1080; 50090-4408
Synonyms Mepivacaine | Mepivacaina Braun | Isogaine | Meaverin | Mecain | Mepihexal | Mepivacain-Injektopas | Mepivacain Injektopas | Mepivacaine Hydrochloride | Mepivacaine Monohydrochloride | Mepivastesin | Polocaine | Scandinibsa | Scandonest | Scandicain | Scandicaine | Carbocaine | Carbocaïne | Isocaine
Chemical Information
Molecular Formula C15H23ClN2O
CAS Registry Number 1722-62-9
SMILES CC1=C(C(=CC=C1)C)NC(=O)C2CCCCN2C.Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Brain hypoxia24.04.06.022; 22.02.02.010; 17.08.02.009--Not Available
Depressed level of consciousness17.02.04.002--
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Hyperhidrosis23.02.03.004; 08.01.03.028--
Loss of consciousness17.02.04.004--Not Available
Nervousness19.06.02.003--Not Available
Oedema14.05.06.010; 08.01.07.006--Not Available
Pulse abnormal13.14.04.004--Not Available
Respiratory arrest22.02.01.009--Not Available
Seizure17.12.03.001--
Skin lesion23.03.03.010--Not Available
Somnolence19.02.05.003; 17.02.04.006--
Swelling08.01.03.015--Not Available
Swelling face23.04.01.018; 10.01.05.018--Not Available
Tremor17.01.06.002--
Urticaria23.04.02.001; 10.01.06.001--
Vision blurred17.17.01.010; 06.02.06.007--
Paraesthesia oral17.02.06.008; 07.05.03.003--Not Available
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