Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Mepenzolate bromide
Drug ID BADD_D01383
Description Mepenzolate is a post-ganglionic parasympathetic inhibitor. It decreases gastric acid and pepsin secretion and suppresses spontaneous contractions of the colon. Mepenzolate diminishes gastric acid and pepsin secretion. Mepenzolate also suppresses spontaneous contractions of the colon. Pharmacologically, it is a post-ganglionic parasympathetic inhibitor. It has not been shown to be effective in contributing to the healing of peptic ulcer, decreasing the rate of recurrence, or preventing complications.
Indications and Usage Not Available
Marketing Status Discontinued
ATC Code A03AB12
DrugBank ID DB04843
KEGG ID D00720
MeSH ID C005101
PubChem ID 6461
TTD Drug ID D0FV3V
NDC Product Code Not Available
Synonyms mepenzolic acid | mepenzolate iodide | mepenzolate bromide | mepenzolic acid, bromine salt | N-methyl-3-piperidylbenzilate methyl bromide | mepenzolate | Cantil | mepenzolate bromide, (+-)-isomer | mepenzolic acid, bromine salt, 1-(methyl-(14)C)-labeled
Chemical Information
Molecular Formula C21H26BrNO3
CAS Registry Number 76-90-4
SMILES C[N+]1(CCCC(C1)OC(=O)C(C2=CC=CC=C2)(C3=CC=CC=C3)O)C.[Br-]
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal distension07.01.04.001--
Ageusia17.02.07.001; 07.14.03.003--Not Available
Anaphylactic reaction24.06.03.006; 10.01.07.001--
Asthenia08.01.01.001--Not Available
Confusional state17.02.03.005; 19.13.01.001--
Constipation07.02.02.001--
Cycloplegia17.17.02.003; 06.05.03.002--Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Dry mouth07.06.01.002--
Headache17.14.01.001--
Hypohidrosis23.02.03.005; 08.01.03.029--
Insomnia19.02.01.002; 17.15.03.002--
Intraocular pressure increased13.07.04.002--Not Available
Mydriasis17.02.11.003; 06.05.03.004--Not Available
Nausea07.01.07.001--
Nervousness19.06.02.003--Not Available
Palpitations02.01.02.003--
Somnolence19.02.05.003; 17.02.04.006--
Suppressed lactation21.05.02.003; 18.06.02.001--Not Available
Tachycardia02.03.02.007--Not Available
Urinary hesitation20.02.02.009--Not Available
Urinary retention20.02.02.011--
Urticaria23.04.02.001; 10.01.06.001--
Vision blurred17.17.01.010; 06.02.06.007--
Vomiting07.01.07.003--
Erectile dysfunction21.03.01.007; 19.08.04.001--
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