Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Menotropins
Drug ID BADD_D01380
Description Menotropins contains follicle stimulating hormone (FSH) and luteinizing hormone (LH) purified from the urine of postmenopausal women. It is used as a fertility medication that is injected either subcutaneously or intramuscularly. It is composed of LH with 2 subunits, alpha = 92 residues, beta = 121 residues and FSH with 2 subunits, alpha = 92 residues, beta=111 residues.
Indications and Usage For the treatment of female infertility
Marketing Status Prescription; Discontinued
ATC Code G03GA02
DrugBank ID DB00032
KEGG ID D02692
MeSH ID D008596
PubChem ID Not Available
TTD Drug ID D04WBY
NDC Product Code 55566-7501; 67657-0004
Synonyms Menotropins | Menotrophin | Gonadotropins, Human Menopausal | Human Menopausal Gonadotropins | Human Menopausal Gonadotropin | Gonadotropin, Human Menopausal | Menopausal Gonadotropin, Human | CP-90033 | CP 90033 | CP90033 | HMG Lepori | Lepori, HMG | HMG Massone | Pergonal-500 | Pergonal 500 | Pergonal500 | Menopur | HMG Ferring | Menogon | Normegon | ORG-31338 | ORG 31338 | ORG31338 | Pergonal | CP-89044 | CP 89044 | CP89044 | Humegon
Chemical Information
Molecular Formula Not Available
CAS Registry Number 9002-68-0
SMILES Not Available
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Ovarian disorder21.11.02.004--Not Available
Ovarian enlargement21.11.02.001--Not Available
Ovarian hyperstimulation syndrome21.11.02.007; 05.05.01.013--Not Available
Pain08.01.08.004--
Pelvic pain21.10.01.001; 20.02.03.007; 07.01.06.012--
Peritoneal haemorrhage24.07.02.016; 07.07.02.001--Not Available
Polydactyly15.11.07.010; 03.11.07.010--Not Available
Pyrexia08.05.02.003--
Rash23.03.13.001--Not Available
Tachycardia02.03.02.007--Not Available
Tachypnoea22.02.01.014--Not Available
Trisomy 2119.21.06.005; 17.03.07.005; 03.12.01.003; 02.08.02.003--Not Available
Vaginal haemorrhage24.07.03.005; 21.08.01.001--
Vomiting07.01.07.003--
Injection site swelling12.07.03.018; 08.02.03.017--Not Available
Reproductive tract hypoplasia, male21.15.01.004; 03.03.01.006--Not Available
Pulmonary vascular disorder24.03.08.003; 22.06.03.002--Not Available
Ovarian neoplasm21.11.01.005; 16.12.06.001--Not Available
Tibial torsion15.11.07.009; 03.11.07.009--Not Available
Adnexal torsion21.11.02.012--Not Available
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